Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5163071 | 0.90 | LMNA (0.41) | LMNAMAPTHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL5163140 | 0.81 | RAB9A (0.42) | LMNAMAPTHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL4835873 | 0.80 | RAB9A (0.45) | LMNAMAPTHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL4832908 | 0.79 | RAB9A (0.51) | LMNAMAPTHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL4168555 | 0.79 | LMNA (0.47) | LMNAMAPTHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL5167738 | 0.78 | LMNA (0.42) | LMNAMAPTHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL4169850 | 0.78 | LMNA (0.51) | LMNAMAPTHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL5164459 | 0.78 | RAB9A (0.44) | LMNAMAPTHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL5167718 | 0.78 | RAB9A (0.44) | LMNAMAPTHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL5166506 | 0.78 | RAB9A (0.47) | LMNAMAPTHPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082561-A1 | Methods For The Preparation Of Alkyl Diaryl Borinates And Complexed Diarylboronic Acids | THE PENNSYLVANIA STATE RESEARCH FOUNDATION | 2009-03-26 | — | — | US | claimed |
| US-20050080048-A1 | Methods for the preparation of alkyl diaryl borinates and complexed diarylboronic acids | PENN STATE RESEARCH FOUNDATION, THE | 2005-04-14 | — | — | US | claimed |
| EP-1463739-A2 | METHODS FOR THE PREPARATION OF ALKYL DIARYL BORINATES AND COMPLEXED DIARYLBORINIC ACIDS | THE PENNSYLVANIA STATE RESEARCH FOUNDATION (US) | 2004-10-06 | — | — | EP | claimed |
| EP-1339725-A2 | DNA METHYL TRANSFERASE INHIBITORS | THE PENN STATE RESEARCH FOUNDATION (US) | 2003-09-03 | — | — | EP | claimed |
| WO-2003059916-A2 | METHODS FOR THE PREPARATION OF ALKYL DIARYL BORINATES AND COMPLEXED DIARYLBORINIC ACIDS | THE PENNSYLVANIA STATE RESEARCH FOUNDATION (US) | 2003-07-24 | — | — | WO | claimed |
| WO-2002044184-A2 | DNA METHYL TRANSFERASE INHIBITORS | THE PENN STATE RESEARCH FOUNDATION (US) | 2002-06-06 | — | — | WO | claimed |
| US-7405304-B2 | Methods for the preparation of alkyl diaryl borinates and complexed diarylboronic acids | THE PENN STATE RESEARCH FOUNDATION (US) | 2008-07-29 | — | — | US | disclosed |
| EP-1339725-B1 | DNA METHYL TRANSFERASE INHIBITORS | PENN STATE RES FOUND (US) | 2006-11-22 | — | — | EP | disclosed |
| US-20050227933-A1 | Treatment of bacterial induced diseases using DNA methyl transferase inhibitors | BENKOVIC STEPHEN J | 2005-10-13 | — | — | US | disclosed |
| US-20050080048-A1 | Methods for the preparation of alkyl diaryl borinates and complexed diarylboronic acids | PENN STATE RESEARCH FOUNDATION, THE | 2005-04-14 | — | — | US | disclosed |
| EP-1463739-A2 | METHODS FOR THE PREPARATION OF ALKYL DIARYL BORINATES AND COMPLEXED DIARYLBORINIC ACIDS | THE PENNSYLVANIA STATE RESEARCH FOUNDATION (US) | 2004-10-06 | — | — | EP | disclosed |
| EP-1339725-A2 | DNA METHYL TRANSFERASE INHIBITORS | THE PENN STATE RESEARCH FOUNDATION (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2003059916-A2 | METHODS FOR THE PREPARATION OF ALKYL DIARYL BORINATES AND COMPLEXED DIARYLBORINIC ACIDS | THE PENNSYLVANIA STATE RESEARCH FOUNDATION (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2002044184-A2 | DNA METHYL TRANSFERASE INHIBITORS | THE PENN STATE RESEARCH FOUNDATION (US) | 2002-06-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082561-A1 | Methods For The Preparation Of Alkyl Diaryl Borinates And Complexed Diarylboronic Acids | BCL6B, BLVRB, SSB | LMNA 447/4885MAPT 4221/4885HPGD 1831/4885 |
| US-20050080048-A1 | Methods for the preparation of alkyl diaryl borinates and complexed diarylboronic acids | BCL6B, BLVRB, SSB | LMNA 447/4885MAPT 4221/4885HPGD 1831/4885 |
| US-20050227933-A1 | Treatment of bacterial induced diseases using DNA methyl transferase inhibitors | DNMT1, TPMT, GNMT | LMNA 3997/4885MAPT 2351/4885HPGD 1054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.