Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4191882 | 0.90 | MAPT (0.53) | MAPK14MAPTMEN1KMT2AKDM4E | |
| SCHEMBL4183893 | 0.83 | KMT2A (0.65) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL4191625 | 0.81 | ALDH1A1 (0.57) | MAPTMEN1KMT2AKDM4ETSHR | |
| SCHEMBL4180097 | 0.80 | MEN1 (0.45) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL4020386 | 0.78 | MAPT (0.59) | MAPK14MAPTMEN1KMT2AKDM4E | |
| SCHEMBL2818704 | 0.76 | MAPT (0.55) | MAPK14MAPTMEN1KMT2AKDM4E | |
| SCHEMBL17141817 | 0.74 | HDAC3 (0.62) | MEN1KMT2AKDM4EGAATSHR | |
| SCHEMBL30622675 | 0.74 | HDAC3 (0.62) | MEN1KMT2AKDM4EGAATSHR | |
| SCHEMBL6013689 | 0.74 | MEN1 (0.70) | MAPK14MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9944135 | 0.74 | MEN1 (0.62) | MAPTMEN1KMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874722-B1 | HYDROXAMIC ACID DERIVATIVES AND THE PREPARATION METHOD THEREOF | AMOREPACIFIC CORP (KR) | 2015-04-08 | — | — | EP | disclosed |
| US-7485750-B2 | Hydroxamic acid derivatives and the preparation method thereof | AMOREPACIFIC CORPORATION (KR) | 2009-02-03 | — | — | US | disclosed |
| US-20080242730-A1 | Hydroxamic Acid Derivatives and the Preparation Method Thereof | AMOREPACIFIC CORPORATION (KR) | 2008-10-02 | — | — | US | disclosed |
| EP-1874722-A1 | HYDROXAMIC ACID DERIVATIVES AND THE PREPARATION METHOD THEREOF | Amorepacific Corporation (KR) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006118380-A1 | HYDROXAMIC ACID DERIVATIVES AND THE PREPARATION METHOD THEREOF | AMOREPACIFIC CORPORATION (KR) | 2006-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242730-A1 | Hydroxamic Acid Derivatives and the Preparation Method Thereof | COL14A1, CUTA, COL2A1 | MAPK14 2175/4885MAPT 4518/4885MEN1 4712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.