SCHEMBL4186927

SCHEMBL4186927

O=P(O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)Oc1cc(O)c(O)c(O)c1O

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 8/20 0.36
INPP5A Q14642 4/20 0.36
INPP5B P32019 1/20 0.36
FDPS P14324 1/20 0.30
BLM P54132 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4172260 1.00 INPPL1 (0.36) INPPL1INPP5AINPP5BFDPSBLM
SCHEMBL4172265 0.85 TDP1 (0.38) INPPL1INPP5AINPP5BFDPSBLM
SCHEMBL4186933 0.85 TDP1 (0.38) INPPL1INPP5AINPP5BFDPSBLM
SCHEMBL28746864 0.83 INPPL1 (0.37) INPPL1INPP5AINPP5BFDPSBLM
SCHEMBL4181366 0.77 FDPS (0.50) INPPL1INPP5AINPP5BFDPSBLM
SCHEMBL5606361 0.76 INPPL1 (0.43) INPPL1INPP5AINPP5BTDP1
SCHEMBL4181363 0.74 FDPS (0.38) INPPL1INPP5AINPP5BFDPSBLM
SCHEMBL6679863 0.72 INPPL1 (0.36) INPPL1INPP5AINPP5BFDPSBLM
SCHEMBL4186090 0.71 TDP1 (0.38) INPPL1INPP5AINPP5BFDPSBLM
SCHEMBL4181918 0.69 INPPL1 (0.45) INPPL1INPP5AINPP5BFDPSBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090098589-A1 Method DUPONT NUTRITION BIOSCIENCES APS (DK) 2009-04-16 US claimed
JP-2008545385-A 2008-12-18 JP claimed
EP-1888771-A2 METHOD FOR DETERMINING PHYTASE ACTIVITY DANISCO A/S (DK) 2008-02-20 EP claimed
WO-2006123254-A2 METHOD FOR DETERMINING PHYTASE ACTIVITY DANISCO A/S (DK) 2006-11-23 WO claimed
US-20090098589-A1 Method DUPONT NUTRITION BIOSCIENCES APS (DK) 2009-04-16 US disclosed
EP-1888771-A2 METHOD FOR DETERMINING PHYTASE ACTIVITY DANISCO A/S (DK) 2008-02-20 EP disclosed
WO-2006123254-A2 METHOD FOR DETERMINING PHYTASE ACTIVITY DANISCO A/S (DK) 2006-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090098589-A1 Method ALPL, PPA1, ITPA INPPL1 40/4885INPP5A 15/4885INPP5B 53/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.