Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3712175 | 0.83 | PAK1 (0.35) | KMT2ACDK4CCND1 | |
| SCHEMBL17066933 | 0.82 | JAK2 (0.33) | KMT2AALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL30881456 | 0.82 | JAK2 (0.33) | KMT2AALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL28793690 | 0.80 | RPS6KA3 (0.33) | KMT2A | |
| SCHEMBL27845067 | 0.80 | RPS6KA3 (0.36) | KMT2ASMN1; SMN2 | |
| SCHEMBL4194087 | 0.76 | LMNA (0.41) | TLR8KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL22638029 | 0.76 | JAK2 (0.48) | — | |
| SCHEMBL7504710 | 0.75 | CDK4 (0.56) | CDK4CCND1 | |
| SCHEMBL24150591 | 0.75 | KMO (0.50) | POLBMAPTSMN1; SMN2 | |
| SCHEMBL20576350 | 0.75 | HRH4 (0.41) | TLR8POLBKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029145-A2 | PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USES | Novartis Ag (CH) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007140222-A2 | PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2007-12-06 | — | — | WO | disclosed |