Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 4/20 | 0.42 |
| ▸ | KDR | P35968 | 7/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.42 |
| ▸ | FLT1 | P17948 | 2/20 | 0.42 |
| ▸ | FLT4 | P35916 | 2/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4184945 | 0.80 | XDH (0.51) | CHRNB4CHRNA3EGFRKDRPDGFRB | |
| SCHEMBL3951733 | 0.75 | MEN1 (0.63) | CHRNB4CHRNA3MEN1KMT2AEGFR | |
| SCHEMBL4566163 | 0.73 | PIM1 (0.50) | — | |
| SCHEMBL4649706 | 0.72 | CNR2 (0.61) | EGFRKDRPDGFRBCDK1HTR3E | |
| SCHEMBL4649605 | 0.72 | CNR2 (0.56) | CHRNB4CHRNA3EGFRKDRCDK1 | |
| SCHEMBL181114 | 0.71 | MEN1 (0.52) | KDM4EMAPTCHRNB4CHRNA3MEN1 | |
| SCHEMBL3957229 | 0.71 | ALDH1A1 (0.56) | KDM4EMAPTMAPK1CHRNB4CHRNA3 | |
| SCHEMBL3951488 | 0.71 | CHRNB4 (0.52) | MAPTCHRNB4CHRNA3MEN1KMT2A | |
| SCHEMBL9402399 | 0.70 | NPC1 (0.56) | ABL1EGFR | |
| SCHEMBL11560161 | 0.69 | HCAR3 (0.70) | CHRNB4CHRNA3MEN1KMT2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090196912-A1 | Pyridinylamines | GPC BOTECH AG (DE) | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090196912-A1 | Pyridinylamines | PRNP, PLPBP, SNCA | KDM4E 2119/4885POLB 1110/4885MAPT 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.