Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4191461 | 0.89 | KCNH2 (0.62) | KCNH2CYP1A2CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL4187538 | 0.80 | KCNH2 (0.64) | KCNH2CYP1A2CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL13426058 | 0.76 | KCNH2 (0.59) | KCNH2CYP1A2CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL31015546 | 0.72 | KDM4E (0.48) | KCNH2CYP1A2CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL1846278 | 0.71 | HDAC1 (0.51) | CYP1A2CYP2D6CYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL4190046 | 0.70 | KCNH2 (0.61) | KCNH2CYP1A2CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL4189065 | 0.69 | ALDH1A1 (0.56) | KCNH2ALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL4189057 | 0.69 | ALPL (0.52) | KCNH2CYP1A2CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL16668814 | 0.69 | RAB9A (0.69) | CYP1A2CYP2D6CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL2469342 | 0.69 | HIF1A (0.59) | CYP1A2CYP2D6CYP3A4CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090196912-A1 | Pyridinylamines | GPC BOTECH AG (DE) | 2009-08-06 | — | — | US | disclosed |
| EP-1789393-A2 | PYRIDINYLAMINES | GPC Biotech AG (DE) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006010637-A2 | PYRIDINYLAMINES | GPC BIOTECH AG (DE) | 2006-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090196912-A1 | Pyridinylamines | PRNP, PLPBP, SNCA | KCNH2 763/4885CYP1A2 775/4885CYP2D6 842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.