SCHEMBL4187677

SCHEMBL4187677

[Li]C(=O)c1ccc(C)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.62
CES2 O00748 3/20 0.62
CES1 P23141 3/20 0.62
LMNA P02545 3/20 0.62
SMN1; SMN2 Q16637 3/20 0.59
HTT P42858 3/20 0.54
NPSR1 Q6W5P4 3/20 0.54
PKM P14618 3/20 0.54
TDP1 Q9NUW8 3/20 0.54
KMT2A Q03164 3/20 0.54
ATM Q13315 2/20 0.54
HPGD P15428 2/20 0.54
MEN1 O00255 2/20 0.54
NLRP1 Q9C000 1/20 0.54
GAA P10253 1/20 0.54
NTSR1 P30989 1/20 0.54
SRD5A2 P31213 1/20 0.52
HDAC1 Q13547 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
GSK3B P49841 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5609868 0.78 ALDH1A1 (0.62) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL167254 0.77 CES2 (1.00) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL52200 0.77 ALDH1A1 (1.00) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL822185 0.77 ALDH1A1 (1.00) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL55409 0.74 SMN1; SMN2 (0.74) ALDH1A1CES2CES1LMNASMN1; SMN2
4-Methylbenzoic Acid SCHEMBL1331178 0.74 ALDH1A1 (1.00) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL721041 0.74 SMN1; SMN2 (0.74) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL6113243 0.74 ALDH1A1 (0.65) ALDH1A1CES2CES1LMNASMN1; SMN2
4-Methylbenzoic Acid SCHEMBL93638 0.74 ALDH1A1 (1.00) ALDH1A1CES2CES1LMNASMN1; SMN2
Terephthalic Acid SCHEMBL526449 0.74 ALDH1A1 (1.00) ALDH1A1CES2CES1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12565550-B2 Polydiene rubbers with functionalized end groups ARLANXEO DEUTSCHLAND GMBH (DE) 2026-03-03 US disclosed
WO-2025242516-A1 BRANCHED DIENE RUBBER ARLANXEO DEUTSCHLAND GMBH (DE) 2025-11-27 WO disclosed
US-12460082-B2 Counter tapered thermoplastic elastomers DYNASOL ELASTÓMEROS, S.A. DE C.V. (MX) 2025-11-04 US disclosed
EP-4126562-B1 POLYDIENE RUBBERS WITH FUNCTIONALIZED END GROUPS ARLANXEO DEUTSCHLAND GMBH (DE) 2025-08-13 EP disclosed
EP-4590725-A1 AMINO- AND SILOXANE-FUNCTIONALIZED POLYMERS ARLANXEO Deutschland GmbH (DE) 2025-07-30 EP disclosed
US-12371514-B2 1-amino-3-(oxyalkylalkoxysilyl)-2-propanol-terminated diene rubbers ARLANXEO DEUTSCHLAND GMBH (DE) 2025-07-29 US disclosed
US-20250145741-A1 FUNCTIONALIZED POLYMERS ARLANXEO DEUTSCHLAND GMBH (DE) 2025-05-08 US disclosed
EP-4540321-A1 COUNTER TAPERED THERMOPLASTIC ELASTOMERS Dynasol Elastómeros, S.A.de C.V. (MX) 2025-04-23 EP disclosed
US-20250115702-A1 MODIFIED DIENE RUBBERS ARLANXEO DEUTSCHLAND GMBH (DE) 2025-04-10 US disclosed
EP-3999552-B1 CARBOXYTERMINATED DIENE RUBBERS ARLANXEO DEUTSCHLAND GMBH (DE) 2025-03-05 EP disclosed
US-8981008-B2 Tapered triblock copolymers DYNASOL ELASTÓMEROS, S.A. DE C.V. (MX) 2015-03-17 US disclosed
US-20130338300-A1 METHANOL-TERMINATED POLYMERS CONTAINING ETHER LANXESS DEUTSCHLAND GMBH (DE) 2013-12-19 US disclosed
US-20130280458-A1 TRIALKYLSILYLOXY-TERMINATED POLYMERS LANXESS DEUTSCHLAND GMBH (DE) 2013-10-24 US disclosed
US-20120196996-A1 Tapered Triblock Copolymers DYNASOL ELASTOMEROS, S.A. DE C.V. (MX) 2012-08-02 US disclosed
EP-1651705-B1 MODIFIED ANIONICALLY POLYMERIZED POLYMERS BASF CORP (US) 2009-12-23 EP disclosed
US-7517934-B2 Modified anionically polymerized polymers BASF CORPORATION (US) 2009-04-14 US disclosed
EP-1651705-A1 MODIFIED ANIONICALLY POLYMERIZED POLYMERS JOHNSON POLYMER, LLC. (US) 2006-05-03 EP disclosed
WO-2005012393-A1 MODIFIED ANIONICALLY POLYMERIZED POLYMERS JOHNSON POLYMER, LLC (US) 2005-02-10 WO disclosed
US-20050027071-A1 MODIFIED ANIONICALLY POLYMERIZED POLYMERS JOHNSON POLYMER, LLC (US) 2005-02-03 US disclosed
EP-0312928-A1 Branched copolymers and their preparation process BASF Aktiengesellschaft (DE) 1989-04-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565550-B2 Polydiene rubbers with functionalized end groups MSR1, NR1H3, NR1H2 ALDH1A1 2345/4885CES2 1598/4885CES1 1118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.