Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.44 |
| ▸ | FADS1 | O60427 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4188146 | 0.91 | LMNA (0.54) | HDAC1TRPV1HDAC3HDAC2KMT2A | |
| SCHEMBL4193646 | 0.91 | ALDH1A1 (0.48) | HDAC1TRPV1HDAC3HDAC2ALDH1A1 | |
| SCHEMBL4190602 | 0.91 | HDAC1 (0.54) | HDAC1TRPV1HDAC3HDAC2ALDH1A1 | |
| SCHEMBL4193715 | 0.90 | KMT2A (0.48) | HDAC1TRPV1HDAC3HDAC2ALDH1A1 | |
| SCHEMBL4197796 | 0.89 | HDAC3 (0.50) | HDAC1TRPV1HDAC3HDAC2ALDH1A1 | |
| SCHEMBL4189678 | 0.89 | TRPV1 (0.49) | HDAC1TRPV1HDAC3HDAC2ALDH1A1 | |
| SCHEMBL4185425 | 0.89 | KMT2A (0.58) | HDAC1TRPV1HDAC3HDAC2ALDH1A1 | |
| SCHEMBL13653257 | 0.87 | TAS1R3 (0.56) | HDAC1TRPV1HDAC3HDAC2TAS1R3 | |
| SCHEMBL4183093 | 0.86 | HDAC3 (0.47) | HDAC1TRPV1HDAC3HDAC2ALDH1A1 | |
| SCHEMBL13653256 | 0.86 | HDAC1 (0.50) | HDAC1TRPV1HDAC3HDAC2TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247590-A1 | Indane amides | BAYER PHARMACEUTICLAS CORPORATION (US) | 2009-10-01 | — | — | US | disclosed |
| US-20090247590-A1 | Indane amides | BAYER PHARMACEUTICLAS CORPORATION (US) | 2009-10-01 | — | — | US | disclosed |
| US-20090247590-A1 | Indane amides | BAYER PHARMACEUTICLAS CORPORATION (US) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247590-A1 | Indane amides | MKI67, PPIP5K2, CCNA1 | HDAC1 579/4885TRPV1 2361/4885HDAC3 1045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.