Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 9/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 4/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL2685962 | 0.99 | GUSB (0.46) | GUSBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13599332 | 0.89 | GUSB (0.47) | GUSBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4579536 | 0.86 | GUSB (0.63) | GUSBKDM4EHPGDCYP1A1CYP1B1 | |
| Ammonia Solution, Strong SCHEMBL2685964 | 0.84 | GUSB (0.49) | GUSBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2685097 | 0.79 | GUSB (0.70) | GUSBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2730504 | 0.77 | GUSB (0.49) | GUSBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4080440 | 0.77 | TUBB4A (0.52) | GUSBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4085165 | 0.77 | TUBB4A (0.52) | GUSBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1232936 | 0.77 | TNKS (0.49) | GUSBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29351150 | 0.77 | TNKS (0.49) | GUSBTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168159-B2 | Compounds for tumor diagnosis and therapy | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-05-01 | — | — | US | disclosed |