SCHEMBL4188311

SCHEMBL4188311

C[C@H](CC1CCCCC1)NCc1ccccc1NS(=O)(=O)c1ccc2[nH]c(=O)oc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 6/20 0.47
ALPL P05186 5/20 0.47
KMT2A Q03164 4/20 0.47
ALPI P09923 3/20 0.47
ALPG P10696 3/20 0.47
GAA P10253 2/20 0.47
MEN1 O00255 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MAPT P10636 4/20 0.45
TDP1 Q9NUW8 3/20 0.44
TSHR P16473 1/20 0.44
THRB P10828 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
KDM4E B2RXH2 1/20 0.43
PKM P14618 1/20 0.43
LMNA P02545 2/20 0.42
ALDH1A1 P00352 1/20 0.40
TP53 P04637 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4197662 1.00 POLB (0.47) POLBALPLKMT2AALPIALPG
SCHEMBL4197689 1.00 POLB (0.47) POLBALPLKMT2AALPIALPG
SCHEMBL4194569 0.99 POLB (0.48) POLBALPLKMT2AALPIALPG
SCHEMBL4192388 0.93 KDM4E (0.43) POLBALPLKMT2AALPIALPG
SCHEMBL4200065 0.92 KMT2A (0.42) POLBALPLKMT2AALPIALPG
SCHEMBL4192891 0.84 POLB (0.52) POLBKMT2AMEN1MAPTTDP1
SCHEMBL4202106 0.83 PDE3A (0.46) POLBKMT2AGAAMEN1L3MBTL1
SCHEMBL4186036 0.83 POLB (0.52) POLBKMT2AMEN1MAPTTDP1
SCHEMBL4193848 0.82 PDE3A (0.46) POLBKMT2AGAAMEN1MAPT
Cyclohexane SCHEMBL4198292 0.81 KMT2A (0.47) POLBALPLKMT2AALPIALPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP claimed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US claimed
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP disclosed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US disclosed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215764-A1 Antimicrobial agents TUFM, RPS17, HARS1 POLB 215/4885ALPL 1172/4885KMT2A 2047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.