Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 7/20 | 0.52 |
| ▸ | OGT | O15294 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4186036 | 0.99 | POLB (0.52) | POLBOGTTHRBPKMMAPT | |
| SCHEMBL4188311 | 0.84 | POLB (0.47) | POLBTHRBPKMMAPTALDH1A1 | |
| SCHEMBL4197662 | 0.84 | POLB (0.47) | POLBTHRBPKMMAPTALDH1A1 | |
| SCHEMBL4197689 | 0.84 | POLB (0.47) | POLBTHRBPKMMAPTALDH1A1 | |
| SCHEMBL4202106 | 0.84 | PDE3A (0.46) | POLBPKMMAPTALDH1A1TP53 | |
| SCHEMBL4194032 | 0.83 | PKM (0.42) | POLBTHRBPKMMAPTALDH1A1 | |
| SCHEMBL4193848 | 0.83 | PDE3A (0.46) | POLBPKMMAPTALDH1A1TP53 | |
| SCHEMBL4194569 | 0.83 | POLB (0.48) | POLBTHRBPKMMAPTALDH1A1 | |
| SCHEMBL4192388 | 0.82 | KDM4E (0.43) | POLBTHRBPKMMAPTALDH1A1 | |
| SCHEMBL4192303 | 0.82 | BRPF1 (0.50) | PKMALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879877-B1 | ANTIMICROBIAL AGENTS | RANBAXY LAB LTD (IN) | 2013-01-02 | — | — | EP | claimed |
| US-8076370-B2 | Antimicrobial agents | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-13 | — | — | US | claimed |
| US-20090215764-A1 | Antimicrobial agents | RANBAXY LABORATORIES LIMITED (IN) | 2009-08-27 | — | — | US | claimed |
| CN-101203504-A | Antimicrobial agents | RANBAXY LAB LTD (IN) | 2008-06-18 | — | — | CN | claimed |
| EP-1879877-B1 | ANTIMICROBIAL AGENTS | RANBAXY LAB LTD (IN) | 2013-01-02 | — | — | EP | disclosed |
| US-8076370-B2 | Antimicrobial agents | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-13 | — | — | US | disclosed |
| US-20090215764-A1 | Antimicrobial agents | RANBAXY LABORATORIES LIMITED (IN) | 2009-08-27 | — | — | US | disclosed |
| CN-101203504-A | Antimicrobial agents | RANBAXY LAB LTD (IN) | 2008-06-18 | — | — | CN | disclosed |
| EP-1879877-A2 | ANTIMICROBIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117762-A2 | ANTIMICROBIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215764-A1 | Antimicrobial agents | TUFM, RPS17, HARS1 | POLB 215/4885OGT 1548/4885THRB 1214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.