Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4491202 | 0.73 | LMNA (0.41) | LMNAL3MBTL1 | |
| SCHEMBL1447382 | 0.72 | LMNA (0.54) | LMNAL3MBTL1 | |
| SCHEMBL4509021 | 0.72 | LMNA (0.39) | LMNAL3MBTL1 | |
| SCHEMBL4251064 | 0.71 | LMNA (0.52) | LMNAL3MBTL1 | |
| SCHEMBL4025575 | 0.71 | LMNA (0.51) | LMNAL3MBTL1 | |
| SCHEMBL4027824 | 0.67 | LMNA (0.45) | LMNAL3MBTL1 | |
| SCHEMBL4699617 | 0.66 | PIK3CD (0.33) | LMNAUSP2L3MBTL1 | |
| SCHEMBL4247716 | 0.63 | LMNA (0.41) | LMNA | |
| SCHEMBL19586468 | 0.61 | ALDH1A1 (0.38) | USP2L3MBTL1 | |
| SCHEMBL3836602 | 0.61 | ALDH1A1 (0.38) | USP2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032559-A1 | 2-HETEROCYCLOAMINO-4-IMIDAZOLYLPYRIMIDINES AS AGENTS FOR THE INHIBITION OF CELL PROLIFERATION | AstraZeneca AB (SE) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007138268-A1 | 2-HETEROCYCLOAMINO-4-IMIDAZOLYLPYRIMIDINES AS AGENTS FOR THE INHIBITION OF CELL PROLIFERATION | ASTRAZENECA AB (SE) | 2007-12-06 | — | — | WO | disclosed |