SCHEMBL4189013

SCHEMBL4189013

CC(C)(C)OC(=O)C(=O)C1(C)CCNCC1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4372862 0.82 FFAR3 (0.34) KDM4EKMT2A
Hydrochloric Acid SCHEMBL23211002 0.81 FFAR3 (0.33) KDM4EKMT2A
SCHEMBL3218399 0.79 KDM4E (0.33) KDM4EKMT2A
SCHEMBL17040615 0.76
SCHEMBL15055670 0.74 KDM4E (0.35) KDM4EKMT2A
SCHEMBL984738 0.73 KDM4E (0.36) KDM4EKMT2A
SCHEMBL6216344 0.73 OPRM1 (0.55) KMT2A
SCHEMBL28840051 0.72 KDM4E (0.32) KDM4EKMT2A
SCHEMBL28487708 0.71 KDM4E (0.33) KDM4EKMT2A
SCHEMBL4202715 0.70 ALDH1A1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2032559-A1 2-HETEROCYCLOAMINO-4-IMIDAZOLYLPYRIMIDINES AS AGENTS FOR THE INHIBITION OF CELL PROLIFERATION AstraZeneca AB (SE) 2009-03-11 EP claimed
WO-2007138268-A1 2-HETEROCYCLOAMINO-4-IMIDAZOLYLPYRIMIDINES AS AGENTS FOR THE INHIBITION OF CELL PROLIFERATION ASTRAZENECA AB (SE) 2007-12-06 WO claimed