Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1595818 | 0.80 | APLNR (0.42) | NPC1RAB9ASMN1; SMN2APLNR | |
| SCHEMBL9461588 | 0.75 | NPC1 (0.34) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29773168 | 0.75 | NPC1 (0.34) | NPC1RAB9ASMN1; SMN2GAAAPLNR | |
| SCHEMBL1059993 | 0.73 | — | — | |
| SCHEMBL14341603 | 0.70 | NPC1 (0.30) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1871785 | 0.69 | — | — | |
| SCHEMBL8161445 | 0.67 | — | — | |
| SCHEMBL8161448 | 0.67 | — | — | |
| SCHEMBL8161450 | 0.67 | — | — | |
| SCHEMBL15520286 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090076062-A1 | Organic Compounds | MAIBAUM JUERGEN KLAUS | 2009-03-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076062-A1 | Organic Compounds | AGTR1, AGTR2, REN | NPC1 527/4885RAB9A 1656/4885SMN1; SMN2 2362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.