Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL740254 | 0.88 | ALDH1A1 (0.51) | PREPALDH1A1GAAHPGDLMNA | |
| SCHEMBL29354123 | 0.88 | ALDH1A1 (0.51) | PREPALDH1A1GAAHPGDLMNA | |
| SCHEMBL30377081 | 0.88 | ALDH1A1 (0.51) | PREPALDH1A1GAAHPGDLMNA | |
| SCHEMBL4189547 | 0.85 | PREP (0.49) | PREPALDH1A1GAAHPGDLMNA | |
| SCHEMBL5264694 | 0.82 | PREP (0.55) | PREPALDH1A1LMNAGFERNPSR1 | |
| SCHEMBL16162942 | 0.81 | KDM4E (0.45) | ALDH1A1GAAMAPTHPGDLMNA | |
| SCHEMBL3364774 | 0.79 | PREP (0.49) | PREPALDH1A1FKBP1AGFERNPSR1 | |
| SCHEMBL15673353 | 0.79 | ATM (0.51) | PREPLMNAPOLBFKBP1A | |
| SCHEMBL24709598 | 0.77 | ALDH1A1 (0.49) | PREPALDH1A1HPGDLMNAGFER | |
| SCHEMBL29350880 | 0.77 | FAP (0.42) | PREPALDH1A1GAAHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090786-A | HALOPYRROLE AMIDATED AMINO ACID USEFUL FOR INHIBITING SERINE PROTEASE ACTIVITY | FONDATECH BENELUX N.V. (BE) | 2000-07-18 | — | — | US | disclosed |
| EP-0764151-A2 | PURIFICATION OF SERINE PROTEASE AND SYNTHETIC INHIBITORS THEREOF | UNIVERSITAIRE INSTELLING ANTWERPEN (BE) | 1997-03-26 | — | — | EP | disclosed |
| WO-1995034538-A2 | PURIFICATION OF SERINE PROTEASES AND SYNTHETIC INHIBITORS THEREOF | UNIVERSITAIRE INSTELLING ANTWERPEN (BE) | 1995-12-21 | — | — | WO | disclosed |