Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.47 |
| ▸ | RXRB | P28702 | 2/20 | 0.47 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 4/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL305401 | 0.90 | CYP3A4 (0.41) | RXRARXRBLMNAGAACYP3A4 | |
| SCHEMBL26059368 | 0.84 | CYP3A4 (0.53) | KIF11LMNAGAACYP3A4CYP2C19 | |
| SCHEMBL24112628 | 0.82 | SCN5A (0.40) | KIF11LMNACYP2C19MAPTALDH1A1 | |
| SCHEMBL25563995 | 0.82 | KCNN4 (0.50) | PTPN1 | |
| SCHEMBL25564023 | 0.82 | CES2 (0.49) | LMNAGAACYP2C19MAPTALDH1A1 | |
| SCHEMBL42458 | 0.80 | ALDH1A1 (0.56) | CYP3A4CYP2C19HIF1AMAPTTDP1 | |
| SCHEMBL22323537 | 0.80 | RXRA (0.50) | RXRARXRBKIF11PTPN5PTPN1 | |
| SCHEMBL4070722 | 0.78 | CYP2C9 (0.48) | RXRARXRBKIF11PTPN5LMNA | |
| SCHEMBL907993 | 0.78 | GAA (0.39) | RXRARXRBGAACYP3A4CYP2C19 | |
| SCHEMBL305335 | 0.78 | ALDH1A1 (0.39) | LMNAGAACYP3A4CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601775-B2 | Fire retardant resin composition, method of its production, shaped articles comprising the same, and silica | NIPPON SHOKUBAI CO., LTD. (JP) | 2009-10-13 | — | — | US | disclosed |
| US-20060167164-A1 | Fire retardant resin composition, method of its production, shaped articles comprising the same, and silica | NIPPON SHOKUBAI CO., LTD. (JP) | 2006-07-27 | — | — | US | disclosed |
| EP-1507829-A1 | FIRE RETARDANT RESIN COMPOSITION, METHOD OF ITS PRODUCTION, SHAPED ARTICLES COMPRISING THE SAME, AND SILICA | Nippon Shokubai Co., Ltd. (JP) | 2005-02-23 | — | — | EP | disclosed |
| WO-2003099934-A1 | FIRE RETARDANT RESIN COMPOSITION, METHOD OF ITS PRODUCTION, SHAPED ARTICLES COMPRISING THE SAME, AND SILICA | NIPPON SHOKUBAI CO., LTD. (JP) | 2003-12-04 | — | — | WO | disclosed |