Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 12/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4187292 | 0.86 | MARK3 (0.44) | PTGS1PTGS2MGLLFAAHCYP19A1 | |
| SCHEMBL18168629 | 0.78 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL20740487 | 0.75 | PTGS1 (0.34) | PTGS1PTGS2MGLLFAAHCYP19A1 | |
| SCHEMBL4190134 | 0.74 | MARK3 (0.33) | — | |
| SCHEMBL21904551 | 0.73 | DGAT1 (0.32) | — | |
| SCHEMBL4189966 | 0.71 | USP1 (0.38) | PTGS1PTGS2MGLLFAAH | |
| SCHEMBL15301011 | 0.70 | PTGS1 (0.49) | PTGS1PTGS2MGLLFAAHCNR1 | |
| SCHEMBL18211896 | 0.64 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL4187289 | 0.61 | MARK3 (0.46) | — | |
| SCHEMBL7504710 | 0.61 | CDK4 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029145-A2 | PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USES | Novartis Ag (CH) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007140222-A2 | PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2007-12-06 | — | — | WO | disclosed |