Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | BCR | P11274 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4189966 | 0.74 | USP1 (0.38) | SMN1; SMN2ALDH1A1MAPTGAA | |
| SCHEMBL3668641 | 0.66 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1LMNAABL1BCR | |
| SCHEMBL4190137 | 0.64 | PTGS1 (0.36) | — | |
| SCHEMBL4187055 | 0.64 | GLO1 (0.41) | SMN1; SMN2ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL4194087 | 0.64 | LMNA (0.41) | CYP1A2ALDH1A1KMT2ALMNATLR8 | |
| SCHEMBL4196176 | 0.63 | ENPP2 (0.39) | SMN1; SMN2ALDH1A1KMT2AMEN1TLR8 | |
| SCHEMBL31465510 | 0.62 | ADORA2A (0.36) | CYP1A2CYP2C19KMT2AMEN1CYP2C9 | |
| SCHEMBL4191102 | 0.62 | PDE4A (0.39) | ALDH1A1KMT2ATLR8POLB | |
| SCHEMBL13616247 | 0.61 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTABL1BCR | |
| SCHEMBL18168138 | 0.61 | SMN1; SMN2 (0.44) | SMN1; SMN2KMT2AMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3091008-A1 | KINASE INHIBITOR AND USE THEREOF | Xuanzhu Pharma Co., Ltd. (CN) | 2016-11-09 | — | — | EP | disclosed |