Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tert-Butylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5087498 | 0.91 | CA1 (0.42) | CA2CA1 | |
| SCHEMBL17456428 | 0.88 | CA1 (0.44) | CA2CA1TP53 | |
| Methylamine SCHEMBL30182758 | 0.87 | — | — | |
| Hydrazine SCHEMBL11314390 | 0.87 | — | — | |
| SCHEMBL7214 | 0.87 | — | — | |
| Ethylamine SCHEMBL6926078 | 0.84 | CA2 (0.50) | CA2CA1TP53 | |
| Sulfuric Acid SCHEMBL15821656 | 0.84 | CA2 (0.48) | CA2CA1TP53HSD17B10ALDH1A1 | |
| Ethane SCHEMBL9438385 | 0.84 | — | — | |
| SCHEMBL7927312 | 0.84 | — | — | |
| SCHEMBL20637763 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12497341-B2 | Reaction methods for producing nitrogenous phosphoryl compounds that are in situ fluid compositions | SOILGENIC TECHNOLOGIES, LLC (US) | 2025-12-16 | — | — | US | disclosed |
| US-20250340493-A1 | REACTION METHODS FOR PRODUCING NITROGENOUS PHOSPHORYL COMPOUNDS THAT ARE IN SITU FLUID COMPOSITIONS | SOILGENIC TECH LLC (US) | 2025-11-06 | — | — | US | disclosed |
| US-12391623-B2 | Reaction methods for producing nitrogenous phosphoryl compounds that are in situ fluid compositions | SOILGENIC TECHNOLOGIES, LLC (US) | 2025-08-19 | — | — | US | disclosed |
| US-20250197306-A1 | REACTION METHODS FOR PRODUCING NITROGENOUS PHOSPHORYL COMPOUNDS THAT ARE IN SITU FLUID COMPOSITIONS | SOILGENIC TECHNOLOGIES, LLC | 2025-06-19 | — | — | US | disclosed |
| US-12258300-B2 | Reaction methods for producing nitrogenous phosphoryl compounds that are in situ fluid compositions | SOILGENIC TECHNOLOGIES, LLC (US) | 2025-03-25 | — | — | US | disclosed |
| US-20250026695-A1 | REACTION METHODS FOR PRODUCING NITROGENOUS PHOSPHORYL COMPOUNDS THAT ARE IN SITU FLUID COMPOSITIONS | SOILGENIC TECHNOLOGIES, LLC | 2025-01-23 | — | — | US | disclosed |
| US-12098109-B2 | Reaction methods for producing nitrogenous phosphoryl compounds that are in situ fluid compositions | SOILGENIC TECHNOLOGIES, LLC (US) | 2024-09-24 | — | — | US | disclosed |
| EP-4291543-A1 | REACTION METHODS FOR PRODUCING NITROGENOUS PHOSPHORYL COMPOUNDS THAT ARE IN SITU FLUID COMPOSITIONS | Mcknight, Gary, David (US) | 2023-12-20 | — | — | EP | disclosed |
| US-20230140913-A1 | REACTION METHODS FOR PRODUCING NITROGENOUS PHOSPHORYL COMPOUNDS THAT ARE IN SITU FLUID COMPOSITIONS | SOILGENIC TECHNOLOGIES, LLC | 2023-05-11 | — | — | US | disclosed |
| US-20220298083-A1 | REACTION METHODS FOR PRODUCING NITROGENOUS PHOSPHORYL COMPOUNDS THAT ARE IN SITU FLUID COMPOSITIONS | SOILGENIC TECHNOLOGIES, LLC | 2022-09-22 | — | — | US | disclosed |
| US-20080057016-A1 | Conditioning shampoo compositions containing select cationic conditioning polymers | GEARY NICHOLAS W | 2008-03-06 | — | — | US | disclosed |
| US-20070289613-A1 | Conditioning shampoo compositions containing select cationic conditioning polymers | GEARY NICHOLAS W | 2007-12-20 | — | — | US | disclosed |
| EP-0536147-B1 | ANTISTATIC POLYOLEFIN FOAMS AND FILMS AND METHOD OF MAKING THE FOAM AND ANTISTATIC COMPOSITION | DOW CHEMICAL CO (US) | 1996-11-13 | — | — | EP | disclosed |
| EP-0536147-A4 | ANTISTATIC POLYOLEFIN FOAMS AND FILMS AND METHOD OF MAKING THE FOAM AND ANTISTATIC COMPOSITION | — | 1993-06-23 | — | — | EP | disclosed |
| EP-0536147-A1 | ANTISTATIC POLYOLEFIN FOAMS AND FILMS AND METHOD OF MAKING THE FOAM AND ANTISTATIC COMPOSITION. | DOW CHEMICAL CO (US) | 1993-04-14 | — | — | EP | disclosed |
| US-5112528-A | Quaternary Ammonium Salt, Partial Ester of Polyol with Fatty Acid | THE DOW CHEMICAL COMPANY (US) | 1992-05-12 | — | — | US | disclosed |
| US-5110841-A | Synergistic mixture of quaternary ammonium compound and ester of fatty acid with polyol | THE DOW CHEMICAL COMPANY (US) | 1992-05-05 | — | — | US | disclosed |
| WO-1992000346-A1 | ANTISTATIC POLYOLEFIN FOAMS AND FILMS AND METHOD OF MAKING THE FOAM AND ANTISTATIC COMPOSITION | THE DOW CHEMICAL COMPANY (US) | 1992-01-09 | — | — | WO | disclosed |
| US-5071884-A | Mixing plastified polyolefin with partial ester of fatty acid and polyol, blowing agent, quaternary ammonium salt; foaming | THE DOW CHEMICAL COMPANY (US) | 1991-12-10 | — | — | US | disclosed |
| CN-1042201-A | The acidic liquid fabric softener of yellow color that changes to blue upon dilution | PROCTER & GAMBLE (US) | 1990-05-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12098109-B2 | Reaction methods for producing nitrogenous phosphoryl compounds that are in situ fluid compositions | PNP, RNGTT, UPP1 | CA2 328/4885CA1 1159/4885TP53 1948/4885 |
| US-12258300-B2 | Reaction methods for producing nitrogenous phosphoryl compounds that are in situ fluid compositions | PHOSPHO1, PNP, MTAP | CA2 790/4885CA1 720/4885TP53 2934/4885 |
| US-20250026695-A1 | REACTION METHODS FOR PRODUCING NITROGENOUS PHOSPHORYL COMPOUNDS THAT ARE IN SITU FLUID COMPOSITIONS | PHOSPHO1, PNP, MTAP | CA2 790/4885CA1 720/4885TP53 2934/4885 |
| US-12497341-B2 | Reaction methods for producing nitrogenous phosphoryl compounds that are in situ fluid compositions | PHOSPHO1, PNP, MTAP | CA2 790/4885CA1 720/4885TP53 2934/4885 |
| US-20080057016-A1 | Conditioning shampoo compositions containing select cationic conditioning polymers | SGMS2, IMMT, SGMS1 | CA2 3038/4885CA1 1859/4885TP53 2726/4885 |
| US-20250197306-A1 | REACTION METHODS FOR PRODUCING NITROGENOUS PHOSPHORYL COMPOUNDS THAT ARE IN SITU FLUID COMPOSITIONS | PHOSPHO1, PNP, MTAP | CA2 790/4885CA1 720/4885TP53 2934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.