SCHEMBL4190889

SCHEMBL4190889

C=C(C)C(=O)OC(COc1ccc2ccccc2c1)COc1cccc(OC)c1OCC(COc1ccc2ccccc2c1)OC(=O)C(=C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
LMNA P02545 2/20 0.38
MAPT P10636 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPK1 P28482 1/20 0.38
TP53 P04637 1/20 0.38
HSD17B10 Q99714 1/20 0.38
RAPGEF3 O95398 1/20 0.37
RECQL P46063 1/20 0.37
PTPN7 P35236 1/20 0.37
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
POLB P06746 1/20 0.36
PPARG P37231 1/20 0.36
NCOA2 Q15596 1/20 0.36
NCOA1 Q15788 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
NCOA3 Q9Y6Q9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4204699 0.89 PTPN7 (0.43) MEN1KMT2ALMNAALDH1A1MAPK1
SCHEMBL4196017 0.86 PTPN7 (0.41) MEN1KMT2ALMNAALDH1A1MAPK1
SCHEMBL4190458 0.85 PTPN7 (0.44) MEN1KMT2ALMNAALDH1A1MAPK1
SCHEMBL4193366 0.85 PTPN7 (0.47) MEN1KMT2ALMNAALDH1A1MAPK1
SCHEMBL4198425 0.82 PTPN7 (0.43) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL4198175 0.82 CD209 (0.39) MEN1KMT2ALMNAMAPTL3MBTL1
SCHEMBL4198600 0.82 MAPK1 (0.40) MEN1KMT2ALMNAALDH1A1MAPK1
SCHEMBL25123427 0.80 RAB9A (0.42) MEN1KMT2ALMNAL3MBTL1ALDH1A1
SCHEMBL4194263 0.80 NR2E1 (0.45) MEN1KMT2ALMNAALDH1A1MAPK1
SCHEMBL4194783 0.79 CYP1A2 (0.44) MEN1KMT2ALMNAALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1627867-B1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF MITSUI CHEMICALS INC (JP) 2016-01-20 EP disclosed
US-7534909-B2 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2009-05-19 US disclosed
US-20070078198-A1 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2007-04-05 US disclosed
EP-1627867-A1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2006-02-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070078198-A1 (Meth) acrylic ester compound and use thereof METTL14, PAM, TAS2R41 MEN1 744/4885KMT2A 266/4885LMNA 4549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.