SCHEMBL4198600

SCHEMBL4198600

C=C(C)C(=O)OC(COc1ccc2ccccc2c1)COc1c(C)cc(-c2cc(C)c(OCC(COc3ccc4ccccc4c3)OC(=O)C(=C)C)c(C)c2)cc1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.40
PTPN7 P35236 1/20 0.39
RAB9A P51151 4/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
POLB P06746 2/20 0.37
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
KDM1A O60341 1/20 0.37
RECQL P46063 1/20 0.37
HTT P42858 2/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
CASP3 P42574 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
PPARG P37231 3/20 0.36
NCOA2 Q15596 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4198613 0.89 THRB (0.43) POLBLMNAPPARGPPARA
SCHEMBL4193366 0.88 PTPN7 (0.47) MAPK1PTPN7RAB9AMEN1KMT2A
SCHEMBL4197210 0.88 MAPT (0.41) RAB9ANPC1LMNAPPARGPPARD
SCHEMBL4198425 0.87 PTPN7 (0.43) MAPK1PTPN7RAB9AMEN1KMT2A
SCHEMBL4194741 0.87 THRB (0.40) POLBPPARGPPARA
SCHEMBL4190458 0.86 PTPN7 (0.44) MAPK1PTPN7RAB9AMEN1KMT2A
SCHEMBL4202672 0.86 RXRA (0.42) PPARGPPARA
SCHEMBL13017875 0.85 MAPK1 (0.37) MAPK1PTPN7RAB9AMEN1KMT2A
SCHEMBL4204699 0.85 PTPN7 (0.43) MAPK1PTPN7RAB9AMEN1KMT2A
SCHEMBL4191201 0.84 MEN1 (0.40) MAPK1PTPN7RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1627867-B1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF MITSUI CHEMICALS INC (JP) 2016-01-20 EP disclosed
US-7534909-B2 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2009-05-19 US disclosed
US-20070078198-A1 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2007-04-05 US disclosed
EP-1627867-A1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2006-02-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070078198-A1 (Meth) acrylic ester compound and use thereof METTL14, PAM, TAS2R41 MAPK1 1412/4885PTPN7 4180/4885RAB9A 2207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.