Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.46 |
| ▸ | CTSK | P43235 | 6/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 7/20 | 0.44 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25266674 | 1.00 | CTSS (0.46) | CTSSCTSKCYP2D6PPARAPPARG | |
| SCHEMBL26986424 | 0.89 | CTSK (0.44) | CTSSCTSKCYP2D6PPARAPPARG | |
| SCHEMBL27017535 | 0.89 | CTSK (0.44) | CTSSCTSKCYP2D6PPARAPPARG | |
| SCHEMBL2156607 | 0.85 | CTSS (0.47) | CTSSCTSKCYP2D6PPARAPPARG | |
| SCHEMBL2156601 | 0.85 | CTSS (0.47) | CTSSCTSKCYP2D6PPARAPPARG | |
| SCHEMBL7208742 | 0.85 | CTSS (0.47) | CTSSCTSKCYP2D6PPARAPPARG | |
| SCHEMBL1486220 | 0.83 | CTSS (0.50) | CTSSCTSKCYP2D6PPARAPPARG | |
| SCHEMBL688341 | 0.83 | CTSS (0.50) | CTSSCTSKCYP2D6PPARAPPARG | |
| SCHEMBL3323682 | 0.83 | CTSS (0.50) | CTSSCTSKCYP2D6PPARAPPARG | |
| SCHEMBL3682214 | 0.81 | CYP2D6 (0.55) | CTSSCTSKCYP2D6PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159548-A | Antiviral compounds | 安力高医药股份有限公司 | 2024-06-07 | — | — | CN | disclosed |
| US-20230159453-A1 | INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | COCRYSTAL PHARMA, INC. | 2023-05-25 | — | — | US | disclosed |
| CN-115698035-A | Inhibitors of norovirus and coronavirus replication | 共晶制药公司 | 2023-02-03 | — | — | CN | disclosed |
| EP-1554235-B1 | PROCESS FOR SYNTHESIZING L-Y-METHYLENE GLUTAMIC ACID AND ANALOGS | BIONUMERIK PHARMACEUTICALS INC (US) | 2009-02-18 | — | — | EP | disclosed |
| EP-1554235-A4 | PROCESS FOR SYNTHESIZING L-Y-METHYLENE GLUTAMIC ACID AND ANALOGS | BIONUMERIK PHARMACEUTICALS INC (US) | 2007-04-04 | — | — | EP | disclosed |
| US-6977311-B2 | Process for synthesizing L-γ-methylene glutamic acid and analogs | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2005-12-20 | — | — | US | disclosed |
| EP-1554235-A2 | PROCESS FOR SYNTHESIZING L-Y-METHYLENE GLUTAMIC ACID AND ANALOGS | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2005-07-20 | — | — | EP | disclosed |
| US-20040106826-A1 | Process for synthesizing L--methylene glutamic acid and analogs | BIONUMERIK PHARMACEUTICALS, INC. | 2004-06-03 | — | — | US | disclosed |
| WO-2004039314-A2 | PROCESS FOR SYNTHESIZING L-Y-METHYLENE GLUTAMIC ACID AND ANALOGS | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2004-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159453-A1 | INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | VIM, ACE, ACE2 | CTSS 135/4885CTSK 2355/4885CYP2D6 1394/4885 |
| US-20040106826-A1 | Process for synthesizing L--methylene glutamic acid and analogs | GLUL, QPCT, RIMKLA | CTSS 2673/4885CTSK 2100/4885CYP2D6 1475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.