SCHEMBL3323682

SCHEMBL3323682

CC(C)(C)OC(=O)NC(CC(=O)O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CTSS P25774 6/20 0.50
CTSK P43235 6/20 0.50
PPARA Q07869 6/20 0.48
PPARG P37231 5/20 0.48
CTSL P07711 1/20 0.48
CTSB P07858 1/20 0.48
ACE P12821 1/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
PPARD Q03181 2/20 0.46
CYP2D6 P10635 1/20 0.45
MEN1 O00255 1/20 0.45
GAA P10253 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1486220 1.00 CTSS (0.50) CTSSCTSKPPARAPPARGCTSL
SCHEMBL688341 1.00 CTSS (0.50) CTSSCTSKPPARAPPARGCTSL
SCHEMBL30797870 0.93 CTSS (0.49) CTSSCTSKPPARAPPARGCTSL
SCHEMBL6735984 0.93 CTSS (0.46) CTSSCTSKPPARAPPARGCTSL
SCHEMBL30797986 0.93 CTSS (0.49) CTSSCTSKPPARAPPARGCTSL
SCHEMBL20267196 0.88 CTSS (0.47) CTSSCTSKPPARAPPARGCTSL
SCHEMBL20267198 0.88 CTSS (0.47) CTSSCTSKPPARAPPARGCTSL
SCHEMBL1235161 0.87 CTSK (0.49) CTSSCTSKPPARAPPARGCTSL
SCHEMBL12486933 0.87 CTSK (0.49) CTSSCTSKPPARAPPARGCTSL
SCHEMBL343678 0.87 CYP2D6 (0.55) CTSSCTSKPPARAPPARGCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 219 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113501947-A Polyester with amino group and preparation method thereof 温州医科大学 2021-10-15 CN claimed
CN-105498838-B A kind of Baeyer Villiger oxidation reaction catalysts and preparation method and application 石家庄学院 2017-11-21 CN claimed
CN-105498838-A Baeyer-Villiger oxidation reaction catalyst and preparation method and application thereof UNIV SHIJIAZHUANG 2016-04-20 CN claimed
CN-103724392-B A kind of preparation method of amino acid phytosterol ester hydrochloride JIANGNAN UNIVERSITY (CN) 2016-03-02 CN claimed
CN-103724392-A Preparation method of amino acid phytosterol ester hydrochloride UNIV JIANGNAN 2014-04-16 CN claimed
CN-102796169-B Double saturated aliphatic chain alcohol Glu-Asp-Gly-Asp tetrapeptide esters and preparation method and application thereof UNIV CAPITAL MEDICAL SCIENCES 2014-01-29 CN claimed
CN-102796171-B Double saturated aliphatic chain alcohol His-Gly-Glu-Asp tetrapeptide esters and preparation method and application thereof UNIV CAPITAL MEDICAL SCIENCES 2014-01-29 CN claimed
CN-102796170-B Double saturated aliphatic chain alcohol His-Gly-Lys-Asp tetrapeptide esters and preparation method and application thereof UNIV CAPITAL MEDICAL SCIENCES 2014-01-29 CN claimed
CN-102796171-A Double saturated aliphatic chain alcohol His-Gly-Glu-Asp tetrapeptide esters and preparation method and application thereof UNIV CAPITAL MEDICAL 2012-11-28 CN claimed
CN-102796170-A Double saturated aliphatic chain alcohol His-Gly-Lys-Asp tetrapeptide esters and preparation method and application thereof UNIV CAPITAL MEDICAL 2012-11-28 CN claimed
CN-102796169-A Double saturated aliphatic chain alcohol Glu-Asp-Gly-Asp tetrapeptide esters and preparation method and application thereof UNIV CAPITAL MEDICAL 2012-11-28 CN claimed
CN-100590068-C Method for preparing primary amine carbon nano tube UNIV TONGJI 2010-02-17 CN claimed
CN-101177259-A Method for preparing primary amine carbon nano tube UNIV TONGJI (CN) 2008-05-14 CN claimed
CN-1241935-C Liquid phase sgnthesis method of thymus pentapeptide UNIV LANZHOU (CN) 2006-02-15 CN claimed
CN-1202131-C Technology of one kettle method for liquid phase synthesizing thymopentapeptide UNIV JILIN (CN) 2005-05-18 CN claimed
CN-1513872-A Liquid phase sgnthesis method of thymus pentapeptide 兰州大学 2004-07-21 CN claimed
CN-1442428-A Technology of one kettle method for liquid phase synthesizing thymopentapeptide UNIV JILIN (CN) 2003-09-17 CN claimed
US-6398857-B1 ACCUSTIC PIEZOELECTRIC; HOT MELT INK JET PRINTING; BENZOIC ACID VEHICLE; ALKYL OR PHENYL CARBOXYLIC ACID VISCOSITY MODIFIER; RETAINS DESIRED HARDNESS XEROX CORPORATION 2002-06-04 US claimed
US-6395077-B1 INKS WITH BENZOYLBENZOIC ACID AND COLORS XEROX CORPORATION 2002-05-28 US claimed
EP-4714961-A2 PRODRUG MODULATORS OF THE INTEGRATED STRESS PATHWAY Calico Life Sciences LLC (US) 2026-03-25 EP disclosed
EP-4209483-B1 PRODRUG MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2025-12-03 EP disclosed
US-20250115634-A1 LIGAND, METHOD FOR PREPARING SAME, AND USE THEREOF LNCTAC CO., LTD. (CN) 2025-04-10 US disclosed
CN-119684406-A Enzyme response self-assembled polypeptide prodrug loaded with camptothecine, preparation and application thereof 东南大学 2025-03-25 CN disclosed
US-20250025438-A1 Derivative of aspartic acid and use thereof in treatment of metabolic diseases such as hepatic fibrosis and non-alcoholic hepatitis SHENZHEN JINGTAI TECHNOLOGY CO., LTD. (CN) 2025-01-23 US disclosed
US-20240208992-A1 MACROCYCLES AS CFTR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2024-06-27 US disclosed
CN-118234705-A Aspartic acid derivative and application thereof in treatment of liver fibrosis, nonalcoholic hepatitis and other metabolic diseases 深圳利沃生物医药科技有限公司 2024-06-21 CN disclosed
US-12005046-B2 Riluzole prodrugs and their use BIOHAVEN THERAPEUTICS LTD. (US) 2024-06-11 US disclosed
US-12005047-B2 Riluzole prodrugs and their use BIOHAVEN THERAPEUTICS LTD. (US) 2024-06-11 US disclosed
CN-118027017-A BRM inhibitor 苏州信诺维医药科技股份有限公司 2024-05-14 CN disclosed
WO-2024056798-A1 MACROCYCLIC CFTR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2024-03-21 WO disclosed
US-20240091205-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE BEETLEJUICE SA LLC, AS PURCHASER AGENT 2024-03-21 US disclosed
US-11911369-B2 Prodrugs of riluzole and their method of use BIOHAVEN THERAPEUTICS LTD. (VG) 2024-02-27 US disclosed
US-20240051985-A1 METTL3 MODULATORS ACCENT THERAPEUTICS INC (US) 2024-02-15 US disclosed
EP-4308575-A1 MACROCYCLES AS CFTR MODULATORS Idorsia Pharmaceuticals Ltd (CH) 2024-01-24 EP disclosed
US-20230381149-A1 RILUZOLE PRODRUGS AND THEIR USE BEETLEJUICE SA LLC, AS PURCHASER AGENT 2023-11-30 US disclosed
US-20230381150-A1 RILUZOLE PRODRUGS AND THEIR USE BEETLEJUICE SA LLC, AS PURCHASER AGENT 2023-11-30 US disclosed
CN-117024476-A diphenylphosphonooxy-X-phenol compound, preparation method and application in preparation of aspartame 西北工业大学 2023-11-10 CN disclosed
CN-116640182-A Transdermal delivery system for polypeptides and related compounds 泰飞尔生物医药(苏州)有限公司 2023-08-25 CN disclosed
WO-2023143374-A1 LIGAND, METHOD FOR PREPARING SAME, AND USE THEREOF 成都凌泰氪生物技术有限公司 2023-08-03 WO disclosed
CN-116283647-A Prodrug modulators that integrate stress pathways 卡里科生命科学有限责任公司 2023-06-23 CN disclosed
CN-116283977-A Inhibitors of αvβ6 integrin 莫菲克医疗股份有限公司 2023-06-23 CN disclosed
WO-2023083291-A1 DERIVATIVE OF ASPARTIC ACID AND USE THEREOF IN TREATMENT OF METABOLIC DISEASES SUCH AS HEPATIC FIBROSIS AND NON-ALCOHOLIC HEPATITIS 深圳利沃生物医药科技有限公司 2023-05-19 WO disclosed
CN-110573499-B Inhibitors of αvβ6 integrin 莫菲克医疗股份有限公司 2023-04-21 CN disclosed
US-20230017637-A1 RILUZOLE PRODRUGS AND THEIR USE BEETLEJUICE SA LLC, AS PURCHASER AGENT 2023-01-19 US disclosed
US-20220396555-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE BIOHAVEN THERAPEUTICS LTD. (US) 2022-12-15 US disclosed
CN-113423685-B Prodrug modulators of integrated stress pathways 卡里科生命科学有限责任公司 2022-11-29 CN disclosed
CN-115053184-A Composition for forming EUV resist underlayer film 日产化学株式会社 2022-09-13 CN disclosed
WO-2022127704-A1 PROCESS FOR PREPARING CARBOXYL CYCLIC ACID ANHYDRIDE 北京大学 2022-06-23 WO disclosed
EP-4011870-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING RILUZOLE PRODRUGS Biohaven Pharmaceutical Holding Company Ltd. (US) 2022-06-15 EP disclosed
CN-109010830-B Application of platelet related inhibitor in preparation of medicine for treating thrombocytopenia 苏州大学 2022-06-07 CN disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
US-11186541-B2 Potent inhibitors of aspartate N-acetyl-transferase for the treatment of Canavan disease THE UNIVERSITY OF TOLEDO (US) 2021-11-30 US disclosed
US-11149043-B2 Prodrug modulators of the integrated stress pathway CALICO LIFE SCIENCES LLC (US) 2021-10-19 US disclosed
CN-113501947-A Polyester with amino group and preparation method thereof 温州医科大学 2021-10-15 CN disclosed
CN-113501947-A Polyester with amino group and preparation method thereof 温州医科大学 2021-10-15 CN disclosed
CN-113423685-A Prodrug modulators of integrated stress pathways 卡里科生命科学有限责任公司 2021-09-21 CN disclosed
US-11091423-B2 Reagents and methods for esterification WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2021-08-17 US disclosed
US-20210236471-A1 RILUZOLE PRODRUGS AND THEIR USE BEETLEJUICE SA LLC, AS PURCHASER AGENT 2021-08-05 US disclosed
US-20210236470-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE BIOHAVEN PHARMACEUTICAL HOLDING COMPANY LTD. 2021-08-05 US disclosed
US-20210230195-A1 PRODRUG MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC 2021-07-29 US disclosed
US-20210228549-A1 RILUZOLE PRODRUGS AND THEIR USE BEETLEJUICE SA LLC, AS PURCHASER AGENT 2021-07-29 US disclosed
US-11052070-B2 Riluzole prodrugs and their use BIOHAVEN THERAPEUTICS LTD. (US) 2021-07-06 US disclosed
CN-112341635-A Emulsifier special for epoxy asphalt, epoxy emulsified asphalt and preparation method of epoxy emulsified asphalt 浙江潮源新型建材股份有限公司 2021-02-09 CN disclosed
US-10905681-B2 Riluzole prodrugs and their use BIOHAVEN THERAPEUTICS LTD. (US) 2021-02-02 US disclosed
US-20200289475-A1 RILUZOLE PRODRUGS AND THEIR USE BEETLEJUICE SA LLC, AS PURCHASER AGENT 2020-09-17 US disclosed
US-20200270202-A1 POTENT INHIBITORS OF ASPARTATE N-ACETYL-TRANSFERASE FOR THE TREATMENT OF CANAVAN DISEASE THE UNIVERSITY OF TOLEDO (US) 2020-08-27 US disclosed
US-20200206362-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS Moderna TX, Inc. (US) 2020-07-02 US disclosed
US-20200190011-A1 Reagents and Methods for Esterification WISCONSIN ALUMNI RESEARCH FOUNDATION 2020-06-18 US disclosed
CN-111164071-A Process for the preparation of intermediate compounds for the synthesis of medicaments 株式会社LG化学 2020-05-15 CN disclosed
US-10639298-B2 Prodrugs of riluzole and their method of use BIOHAVEN THERAPEUTICS LTD. (US) 2020-05-05 US disclosed
WO-2020063824-A1 NITROXOLINE PRODRUG AND USE THEREOF 江苏亚虹医药科技有限公司 2020-04-02 WO disclosed
US-20200085794-A1 RILUZOLE PRODRUGS AND THEIR USE BIOHAVEN THERAPEUTICS LTD. (JP) 2020-03-19 US disclosed
US-10577303-B1 Reagents and methods for esterification WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2020-03-03 US disclosed
US-10556018-B2 Compositions and methods for delivery of agents ARES CAPITAL CORPORATION, AS AGENT 2020-02-11 US disclosed
CN-110526933-A Biotin variants, streptavidin mutants and uses thereof SAVID THERAPEUTICS INC 2019-12-03 CN disclosed
CN-110433130-A A kind of male's basic nursing liquid SHANDONG CHUANYUN BIOTECHNOLOGY CO LTD 2019-11-12 CN disclosed
CN-110312533-A Prodrugs of cytotoxic active agents having an enzymatically cleavable group 拜耳公司 2019-10-08 CN disclosed
CN-104945309-B New nitroso compound and application thereof as nitroxyl donors 卡尔迪奥克斯尔制药公司 2019-06-04 CN disclosed
CN-109705325-A A kind of chirality petchem and preparation method thereof 浙江工业大学 2019-05-03 CN disclosed
CN-106163509-B β -substituted β -amino acids and analogs as chemotherapeutic agents 夸德里加生物科学公司 2019-05-03 CN disclosed
US-20190117798-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS MODERNATX, INC. (US) 2019-04-25 US disclosed
EP-3458479-A1 ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES AbbVie Inc. (US) 2019-03-27 EP disclosed
US-10207010-B2 Compositions and methods for delivery of agents MODERNATX, INC. (US) 2019-02-19 US disclosed
EP-3386484-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS ModernaTX, Inc. (US) 2018-10-17 EP disclosed
US-20180147298-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS MODERNATX, INC. (US) 2018-05-31 US disclosed
CN-108026026-A Beta-amino acids and analog and its application as the β-substituted of chemotherapeutics 夸德里加生物科学公司 2018-05-11 CN disclosed
US-20180036290-A1 RILUZOLE PRODRUGS AND THEIR USE BEETLEJUICE SA LLC, AS PURCHASER AGENT 2018-02-08 US disclosed
US-20180037557-A1 PRODRUGS RILUZOLE AND THEIR METHOD OF USE BEETLEJUICE SA LLC, AS PURCHASER AGENT 2018-02-08 US disclosed
US-20180028664-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS MODERNATX, INC. (US) 2018-02-01 US disclosed
CN-103402516-B Compound, composition and application method as antiviral drugs 富津世生物技术有限公司 2018-01-30 CN disclosed
EP-3265448-A1 RILUZOLE PRODRUGS AND THEIR USE Biohaven Pharmaceutical Holding Company Ltd. (US) 2018-01-10 EP disclosed
CN-107567438-A Riluzole prodrug and application thereof 拜尔哈文制药股份有限公司 2018-01-09 CN disclosed
WO-2017214335-A1 ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES ABBVIE INC. (US) 2017-12-14 WO disclosed
CN-105498838-B A kind of Baeyer Villiger oxidation reaction catalysts and preparation method and application 石家庄学院 2017-11-21 CN disclosed
US-9795678-B2 Fast-acting insulin composition comprising a substituted anionic compound and a polyanionic compound ADOCIA (FR) 2017-10-24 US disclosed
WO-2017172476-A1 POTENT INHIBITORS OF ASPARTATE N-ACETYL-TRANSFERASE FOR THE TREATMENT OF CANAVAN DISEASE THE UNIVERSITY OF TOLEDO (US) 2017-10-05 WO disclosed
WO-2017099823-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS MODERNATX, INC. (US) 2017-06-15 WO disclosed
CN-106459089-A Biotin variants, streptavidin mutants and uses thereof 赛威德医疗公司 2017-02-22 CN disclosed
US-20170028075-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES Ashvattha Therapeutics, Inc. 2017-02-02 US disclosed
US-9526794-B2 Injectable dendrimer hydrogel nanoparticles WAYNE STATE UNIVERSITY (US) 2016-12-27 US disclosed
US-9526794-B2 Injectable dendrimer hydrogel nanoparticles WAYNE STATE UNIVERSITY (US) 2016-12-27 US disclosed
CN-106163509-A Beta-substituted beta-amino acids and analogs as chemotherapeutic agents 夸德里加生物科学公司 2016-11-23 CN disclosed
CN-106132414-A Aryl lactams inhibitors of kinases 百时美施贵宝公司 2016-11-16 CN disclosed
WO-2016140879-A9 RILUZOLE PRODRUGS AND THEIR USE BIOHAVEN PHARMACEUTICAL HOLDING COMPANY LTD. (US) 2016-11-03 WO disclosed
WO-2016140878-A9 PRODRUGS RILUZOLE AND THEIR METHOD OF USE BIOHAVEN PHARMACEUTICAL HOLDING COMPANY LTD. (US) 2016-10-20 WO disclosed
CN-102453001-B Thiomorpholine compounds and its production and use INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2016-06-01 CN disclosed
CN-104136997-B Composition for forming highly adhesive resist underlayer film NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-05-11 CN disclosed
CN-105498838-A Baeyer-Villiger oxidation reaction catalyst and preparation method and application thereof UNIV SHIJIAZHUANG 2016-04-20 CN disclosed
CN-105498838-A Baeyer-Villiger oxidation reaction catalyst and preparation method and application thereof UNIV SHIJIAZHUANG 2016-04-20 CN disclosed
US-9195137-B2 Composition for forming highly adhesive resist underlayer film NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-11-24 US disclosed
US-9195137-B2 Composition for forming highly adhesive resist underlayer film NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-11-24 US disclosed
WO-2015125820-A1 BIOTIN VARIANT, STREPTAVIDIN MUTANT, AND USES THEREOF サヴィッド・セラピューティックス株式会社 2015-08-27 WO disclosed
US-20150031206-A1 COMPOSITION FOR FORMING HIGHLY ADHESIVE RESIST UNDERLAYER FILM NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-01-29 US disclosed
US-20150031206-A1 COMPOSITION FOR FORMING HIGHLY ADHESIVE RESIST UNDERLAYER FILM NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-01-29 US disclosed
CN-102548993-B Cyclic (aza)indolizinecarboxamides, their preparation and their use as pharmaceuticals SANOFI AVENTIS 2014-12-10 CN disclosed
WO-2014186465-A1 ANTI-INFLUENZA COMPOSITIONS AND METHODS BIOCRYST PHARMACEUTICALS, INC. (US) 2014-11-20 WO disclosed
CN-104136997-A Composition for forming highly adhesive resist underlayer film NISSAN CHEMICAL IND LTD 2014-11-05 CN disclosed
CN-103896923-A Blood sugar reducing compound, preparation method of blood sugar reducing compound, medicine composition including blood sugar reducing compound and application of medicine composition BEIJING LABSOLUTIONS PHARMACEUTICALS CO LTD 2014-07-02 CN disclosed
US-8735582-B2 Method for producing carboxylic anhydride and arylboronic acid compound NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2014-05-27 US disclosed
CN-102796169-B Double saturated aliphatic chain alcohol Glu-Asp-Gly-Asp tetrapeptide esters and preparation method and application thereof UNIV CAPITAL MEDICAL SCIENCES 2014-01-29 CN disclosed
CN-102796171-B Double saturated aliphatic chain alcohol His-Gly-Glu-Asp tetrapeptide esters and preparation method and application thereof UNIV CAPITAL MEDICAL SCIENCES 2014-01-29 CN disclosed
CN-102796170-B Double saturated aliphatic chain alcohol His-Gly-Lys-Asp tetrapeptide esters and preparation method and application thereof UNIV CAPITAL MEDICAL SCIENCES 2014-01-29 CN disclosed
CN-103402516-A Compounds useful as antiviral agents, compositions, and methods of use FUZIANS BIOMEDICALS INC 2013-11-20 CN disclosed
CN-103402975-A Beta-hydroxyalkylamide and resin composition TOYO INK SC HOLDINGS CO LTD 2013-11-20 CN disclosed
EP-2459557-B1 CYCLIC (AZA)INDOLIZINECARBOXAMIDES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS SANOFI SA (FR) 2013-09-18 EP disclosed
US-20130136697-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES NATIONAL INSTITUTES OF HEALTH (US) 2013-05-30 US disclosed
US-20130136697-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES NATIONAL INSTITUTES OF HEALTH (US) 2013-05-30 US disclosed
US-8415336-B2 Cyclic (aza)indolizinecarboxamides, their preparation and their use as pharmaceuticals SANOFI (FR) 2013-04-09 US disclosed
US-8343999-B2 Thiazolyl compounds useful as kinase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2013-01-01 US disclosed
CN-102796171-A Double saturated aliphatic chain alcohol His-Gly-Glu-Asp tetrapeptide esters and preparation method and application thereof UNIV CAPITAL MEDICAL 2012-11-28 CN disclosed
CN-102796170-A Double saturated aliphatic chain alcohol His-Gly-Lys-Asp tetrapeptide esters and preparation method and application thereof UNIV CAPITAL MEDICAL 2012-11-28 CN disclosed
CN-102796169-A Double saturated aliphatic chain alcohol Glu-Asp-Gly-Asp tetrapeptide esters and preparation method and application thereof UNIV CAPITAL MEDICAL 2012-11-28 CN disclosed
US-20120232081-A1 CYCLIC (AZA)INDOLIZINECARBOXAMIDES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS SANOFI (FR) 2012-09-13 US disclosed
CN-102595888-A Single diastereomers of 4-fluoroglutamine and methods for their preparation and use UNIV PENNSYLVANIA 2012-07-18 CN disclosed
CN-102548993-A Cyclic (aza)indolizinecarboxamides, their preparation and their use as pharmaceuticals SANOFI AVENTIS 2012-07-04 CN disclosed
EP-2459557-A1 CYCLIC (AZA)INDOLIZINECARBOXAMIDES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS SANOFI (FR) 2012-06-06 EP disclosed
CN-102453001-A Thiomorpholine compound and preparation method and application thereof INST MATERIA MEDICA CAMS 2012-05-16 CN disclosed
EP-1963319-B1 HETEROARYLPYRROLOPYRIDINONES ACTIVE AS KINASE INHIBITORS NERVIANO MEDICAL SCIENCES SRL (IT) 2012-04-11 EP disclosed
EP-1963319-B1 HETEROARYLPYRROLOPYRIDINONES ACTIVE AS KINASE INHIBITORS NERVIANO MEDICAL SCIENCES SRL (IT) 2012-04-11 EP disclosed
US-7842626-B2 Partially fluorinated compositions and surface active agents E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-11-30 US disclosed
US-7842626-B2 Partially fluorinated compositions and surface active agents E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-11-30 US disclosed
US-7781443-B2 cholesteryl ester transfer protein (CETP) anatgonists such as 2R,4S)-4-{[3,5-Bis(trifluoromethyl)benzyl]-[5-(morpholin-4-yl)pyrimidin-2-yl]}amino-2-ethyl-6-methoxy-3,4-dihydro-2H-[1,5]naphthyridine-1-carboxylic acid ethyl ester, having improved bioavailability MITSUBISHI TANABE PHARMA CORPORATION (JP) 2010-08-24 US disclosed
US-20100120770-A1 THIAZOLYL COMPOUNDS USEFUL AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY 2010-05-13 US disclosed
CN-100590068-C Method for preparing primary amine carbon nano tube UNIV TONGJI 2010-02-17 CN disclosed
EP-2132203-A1 THIAZOLYL COMPOUNDS USEFUL AS KINASE INHIBITORS Bristol-Myers Squibb Company (US) 2009-12-16 EP disclosed
US-7618982-B2 Heteroarylpyrrolopyridinones active as kinase inhibitors NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2009-11-17 US disclosed
US-7618982-B2 Heteroarylpyrrolopyridinones active as kinase inhibitors NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2009-11-17 US disclosed
US-7618982-B2 Heteroarylpyrrolopyridinones active as kinase inhibitors NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2009-11-17 US disclosed
US-20090111737-A1 Novel antibacterial agents THERAVANCE BIOPHARMA ANTIBIOTICS IP, LLC 2009-04-30 US disclosed
US-7473658-B2 Partially fluorinated amino acid derivatives as gelling and surface active agents E. I. DU PONT NEMOURS AND COMPANY (US) 2009-01-06 US disclosed
US-7473658-B2 Partially fluorinated amino acid derivatives as gelling and surface active agents E. I. DU PONT NEMOURS AND COMPANY (US) 2009-01-06 US disclosed
WO-2008124757-A1 THIAZOLYL COMPOUNDS USEFUL AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2008-10-16 WO disclosed
EP-1444202-B1 NOVEL METALLOPROTEINASE INHIBITORS ASTRAZENECA AB (SE) 2008-10-15 EP disclosed
US-20080113172-A1 Partially fluorinated compositions and surface active agents E. I. DU PONT DE NEMOURS AND COMPANY 2008-05-15 US disclosed
US-20080113172-A1 Partially fluorinated compositions and surface active agents E. I. DU PONT DE NEMOURS AND COMPANY 2008-05-15 US disclosed
US-20080113573-A1 Partially fluorinated amino acid derivatives as gelling and surface active agents E. I. DU PONT DE NEMOURS AND COMPANY 2008-05-15 US disclosed
US-20080113573-A1 Partially fluorinated amino acid derivatives as gelling and surface active agents E. I. DU PONT DE NEMOURS AND COMPANY 2008-05-15 US disclosed
CN-101177259-A Method for preparing primary amine carbon nano tube UNIV TONGJI (CN) 2008-05-14 CN disclosed
US-RE39991-E1 Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation DOW AGROSCIENCES LLC (US) 2008-01-01 US disclosed
US-7288537-B2 Azetidine derivatives as CCR-3 receptor antagonists NOVARTIS AG (CH) 2007-10-30 US disclosed
US-7288623-B2 Cyclic peptide tube THE SCRIPPS RESEARCH INSTITUTE (US) 2007-10-30 US disclosed
US-20070154948-A1 Novel antibacterial agents THERAVANCE BIOPHARMA ANTIBIOTICS IP, LLC 2007-07-05 US disclosed
US-20070154948-A1 Novel antibacterial agents THERAVANCE BIOPHARMA ANTIBIOTICS IP, LLC 2007-07-05 US disclosed
WO-2007071621-A1 HETEROARYLPYRROLOPYRIDINONES ACTIVE AS KINASE INHIBITORS NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2007-06-28 WO disclosed
US-20070142415-A1 Heteroarylpyrrolopyridinones active as kinase inhibitors PHARMACIA ITALIA S.P.A. (IT) 2007-06-21 US disclosed
US-20070142415-A1 Heteroarylpyrrolopyridinones active as kinase inhibitors PHARMACIA ITALIA S.P.A. (IT) 2007-06-21 US disclosed
US-20070142415-A1 Heteroarylpyrrolopyridinones active as kinase inhibitors PHARMACIA ITALIA S.P.A. (IT) 2007-06-21 US disclosed
US-20070032485-A1 Tetrahydronaphthyridine derivatives and a process for preparing the same TANABE SEIYAKU CO., LTD. 2007-02-08 US disclosed
CN-1906206-A Di-steroidal prodrugs of estradiol GALEN CHEMICALS LTD (US) 2007-01-31 CN disclosed
CN-1906207-A Di-steroidal prodrugs of ethinyl estradiol GALEN CHEMICALS LTD (US) 2007-01-31 CN disclosed
EP-1732924-A2 TETRAHYDRONAPHTHYRIDINE DERIVATIVES AS CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS TANABE SEIYAKU CO., LTD. (JP) 2006-12-20 EP disclosed
EP-1709061-A1 DI-STEROIDAL PRODRUGS OF ETHINYL ESTRADIOL Warner Chilcott Company Inc. (PR) 2006-10-11 EP disclosed
EP-1709060-A1 DI-STEROIDAL PRODRUGS OF ESTRADIOL Warner Chilcott Company Inc. (PR) 2006-10-11 EP disclosed
US-7067504-B2 Di-steroidal prodrugs of ethinyl estradiol WARNER CHILCOTT COMPANY, INC. (US) 2006-06-27 US disclosed
US-7067505-B2 Di-steroidal prodrugs of estradiol WARNER CHILCOTT COMPANY, INC. (US) 2006-06-27 US disclosed
WO-2006044230-A1 WATER SOLUBLE PRODRUGS OF COX-2 INHIBITORS MERCK & CO., INC. (US) 2006-04-27 WO disclosed
CN-1241935-C Liquid phase sgnthesis method of thymus pentapeptide UNIV LANZHOU (CN) 2006-02-15 CN disclosed
WO-2005095395-A2 TETRAHYDRONAPHTHYRIDINE DERIVATIVES AS CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS TANABE SEIYAKU CO., LTD. (JP) 2005-10-13 WO disclosed
US-20050222118-A1 Azetidine derivatives as ccr-3 receptor antagonists NOVARTIS AG (CH) 2005-10-06 US disclosed
WO-2005070950-A1 DI-STEROIDAL PRODRUGS OF ETHINYL ESTRADIOL WARNER CHILCOTT COMPANY, INC. (US) 2005-08-04 WO disclosed
WO-2005070949-A1 DI-STEROIDAL PRODRUGS OF ESTRADIOL WARNER CHILCOTT COMPANY, INC. (US) 2005-08-04 WO disclosed
WO-2005069750-A2 THERAPEUTIC COMPOSITION WITH NANOSCALE ACTIVATION AGENTS HEMOLYTICS, INC. (US) 2005-08-04 WO disclosed
US-20050159399-A1 Di-steroidal prodrugs of estradiol GALEN (CHEMICALS) LIMITED (IE) 2005-07-21 US disclosed
US-20050159609-A1 Di-steroidal prodrugs of ethinyl estradiol GALEN (CHEMICALS) LIMITED (IE) 2005-07-21 US disclosed
CN-1202131-C Technology of one kettle method for liquid phase synthesizing thymopentapeptide UNIV JILIN (CN) 2005-05-18 CN disclosed
EP-1487435-A1 AZETIDINE DERIVATIVES AS CCR-3 RECEPTOR ANTAGONISTS Novartis AG (CH) 2004-12-22 EP disclosed
CN-1513872-A Liquid phase sgnthesis method of thymus pentapeptide 兰州大学 2004-07-21 CN disclosed
CN-1148346-C Hydrazine derivative - 2004-05-05 CN disclosed
US-20040024176-A1 Cyclic peptide tube THE SCRIPPS RESEARCH INSTITUTE 2004-02-05 US disclosed
WO-2003077907-A1 AZETIDINE DERIVATIVES AS CCR-3 RECEPTOR ANTAGONISTS NOVARTIS AG (CH) 2003-09-25 WO disclosed
EP-0723554-B1 CYCLIC PEPTIDE TUBE SCRIPPS RESEARCH INST (US) 2003-09-24 EP disclosed
CN-1442428-A Technology of one kettle method for liquid phase synthesizing thymopentapeptide UNIV JILIN (CN) 2003-09-17 CN disclosed
US-6613875-B1 Cyclic peptide tube THE SCRIPPS RESEARCH INSTITUTE 2003-09-02 US disclosed
US-20020173468-A1 MODIFIED CYTOSTATIC AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2002-11-21 US disclosed
US-6398857-B1 ACCUSTIC PIEZOELECTRIC; HOT MELT INK JET PRINTING; BENZOIC ACID VEHICLE; ALKYL OR PHENYL CARBOXYLIC ACID VISCOSITY MODIFIER; RETAINS DESIRED HARDNESS XEROX CORPORATION 2002-06-04 US disclosed
US-6395077-B1 INKS WITH BENZOYLBENZOIC ACID AND COLORS XEROX CORPORATION 2002-05-28 US disclosed
CN-1309634-A Hydrazine derivs. HOFFMANN LA ROCHE (CH) 2001-08-22 CN disclosed
CN-1233237-A Heteroaryl succinamides and their use as metalloproteinase inhibitors AGOURON PHARMA (US) 1999-10-27 CN disclosed
US-5616788-A FOR SOLID PHASE PEPTIDE SYNTHESIS HYUNDAI PHARM. IND. CO., LTD. (KR) 1997-04-01 US disclosed
EP-0723554-A1 CYCLIC PEPTIDE TUBE THE SCRIPPS RESEARCH INSTITUTE (US) 1996-07-31 EP disclosed
CN-1032212-C N-protected alpha-L-aspartyl-L-methyl phenylalaninate MITSUI TOATSU CHEMICALS (JP) 1996-07-03 CN disclosed
WO-1995010535-A1 CYCLIC PEPTIDE TUBE THE SCRIPPS RESEARCH INSTITUTE (US) 1995-04-20 WO disclosed
CN-1081681-A Amino sugar derivative DAIICHI SEIYAKU CO (JP) 1994-02-09 CN disclosed
US-5190782-A Dietetics NABISCO, INC. (US) 1993-03-02 US disclosed
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US-5017567-A Steroid antiinflammatory SCHERING CORPORATION (US) 1991-05-21 US disclosed
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EP-0367393-A2 New heterocyclic compounds, production and use thereof Takeda Chemical Industries, Ltd. (JP) 1990-05-09 EP disclosed
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US-4906635-A Carboxyalkyl dipeptides as antiglaucoma agents SCHERING CORPORATION (US) 1990-03-06 US disclosed
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US-4778795-A Carboxyalkyl dipeptides as antiglaucoma agents SCHERING CORPORATION (US) 1988-10-18 US disclosed
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Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (49 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080113172-A1 Partially fluorinated compositions and surface active agents FLNB, FLNA, FSCN1 CTSS 2311/4885CTSK 1579/4885PPARA 463/4885
US-20230381150-A1 RILUZOLE PRODRUGS AND THEIR USE APEH, ALDH1A2, UGT1A9 CTSS 653/4885CTSK 586/4885PPARA 4317/4885
US-20050159399-A1 Di-steroidal prodrugs of estradiol CYP19A1, HSD17B11, ESR1 CTSS 1881/4885CTSK 2208/4885PPARA 643/4885
US-10905681-B2 Riluzole prodrugs and their use APEH, ALDH1A2, UGT1A9 CTSS 653/4885CTSK 586/4885PPARA 4317/4885
US-11149043-B2 Prodrug modulators of the integrated stress pathway ATF4, ATF1, DDIT3 CTSS 2876/4885CTSK 3395/4885PPARA 2773/4885
US-20200190011-A1 Reagents and Methods for Esterification ADCY1, ADCY4, ADCY7 CTSS 2857/4885CTSK 2795/4885PPARA 669/4885
US-20040024176-A1 Cyclic peptide tube SGTA, VIP, TIMCC CTSS 4457/4885CTSK 4263/4885PPARA 4307/4885
US-20200289475-A1 RILUZOLE PRODRUGS AND THEIR USE APEH, ALDH1A2, UGT1A9 CTSS 653/4885CTSK 586/4885PPARA 4317/4885
US-20240051985-A1 METTL3 MODULATORS METTL3, METTL16, METTL14 CTSS 4285/4885CTSK 4088/4885PPARA 3704/4885
US-20180036290-A1 RILUZOLE PRODRUGS AND THEIR USE APEH, ALDH1A2, UGT1A9 CTSS 653/4885CTSK 586/4885PPARA 4317/4885
US-20190117798-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS HDLBP, APOB, TSG101 CTSS 2817/4885CTSK 3216/4885PPARA 3086/4885
US-20170028075-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES PAM, UACA, FLT1 CTSS 4799/4885CTSK 4773/4885PPARA 575/4885
US-11091423-B2 Reagents and methods for esterification ADCY1, ADCY4, ADCY7 CTSS 2857/4885CTSK 2795/4885PPARA 669/4885
US-20050222118-A1 Azetidine derivatives as ccr-3 receptor antagonists CCR3, CCR1, CCR9 CTSS 3822/4885CTSK 4155/4885PPARA 1580/4885
US-20210230195-A1 PRODRUG MODULATORS OF THE INTEGRATED STRESS PATHWAY ATF4, ATF1, DDIT3 CTSS 2876/4885CTSK 3395/4885PPARA 2773/4885
US-12005046-B2 Riluzole prodrugs and their use APEH, ALDH1A2, UGT1A9 CTSS 653/4885CTSK 586/4885PPARA 4317/4885
US-20200270202-A1 POTENT INHIBITORS OF ASPARTATE N-ACETYL-TRANSFERASE FOR THE TREATMENT OF CANAVAN DISEASE GOT1, ACAT1, GOT2 CTSS 776/4885CTSK 927/4885PPARA 3673/4885
US-10577303-B1 Reagents and methods for esterification ADCY1, ADCY4, ADCY7 CTSS 2857/4885CTSK 2795/4885PPARA 669/4885
US-11911369-B2 Prodrugs of riluzole and their method of use APEH, UGT1A9, ALDH3A1 CTSS 503/4885CTSK 543/4885PPARA 4402/4885
US-20020173468-A1 MODIFIED CYTOSTATIC AGENTS TP53, PTMS, ANXA5 CTSS 1070/4885CTSK 1403/4885PPARA 1615/4885
US-10556018-B2 Compositions and methods for delivery of agents HDLBP, APOB, TSG101 CTSS 2817/4885CTSK 3216/4885PPARA 3086/4885
US-20200206362-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS HDLBP, APOB, TSG101 CTSS 2817/4885CTSK 3216/4885PPARA 3086/4885
US-12005047-B2 Riluzole prodrugs and their use APEH, ALDH1A2, UGT1A9 CTSS 653/4885CTSK 586/4885PPARA 4317/4885
US-20210236471-A1 RILUZOLE PRODRUGS AND THEIR USE APEH, ALDH1A2, UGT1A9 CTSS 653/4885CTSK 586/4885PPARA 4317/4885
US-10207010-B2 Compositions and methods for delivery of agents HDLBP, APOB, TSG101 CTSS 2817/4885CTSK 3216/4885PPARA 3086/4885
US-20230017637-A1 RILUZOLE PRODRUGS AND THEIR USE APEH, ALDH1A2, UGT1A9 CTSS 653/4885CTSK 586/4885PPARA 4317/4885
US-20070142415-A1 Heteroarylpyrrolopyridinones active as kinase inhibitors MAP3K1, MAP3K19, MAP3K3 CTSS 2183/4885CTSK 1284/4885PPARA 3222/4885
US-11052070-B2 Riluzole prodrugs and their use APEH, ALDH1A2, UGT1A9 CTSS 653/4885CTSK 586/4885PPARA 4317/4885
US-20240208992-A1 MACROCYCLES AS CFTR MODULATORS CFTR, PKD1, ARRB1 CTSS 2999/4885CTSK 2996/4885PPARA 2569/4885
US-20250115634-A1 LIGAND, METHOD FOR PREPARING SAME, AND USE THEREOF SIGLEC7, ASGR1, ADGRF1 CTSS 3075/4885CTSK 3975/4885PPARA 2752/4885
US-20180037557-A1 PRODRUGS RILUZOLE AND THEIR METHOD OF USE APEH, CYP2C9, ALDH1A2 CTSS 440/4885CTSK 416/4885PPARA 4295/4885
US-20100120770-A1 THIAZOLYL COMPOUNDS USEFUL AS KINASE INHIBITORS TTBK1, ERBB2, TEC CTSS 3568/4885CTSK 1326/4885PPARA 2748/4885
US-20130136697-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES UACA, PAM, JAK3 CTSS 4760/4885CTSK 4792/4885PPARA 486/4885
US-20070032485-A1 Tetrahydronaphthyridine derivatives and a process for preparing the same CETP, MTTP, NPC1L1 CTSS 2569/4885CTSK 2574/4885PPARA 3203/4885
US-20050159609-A1 Di-steroidal prodrugs of ethinyl estradiol ESR1, HSD17B11, CYP19A1 CTSS 1637/4885CTSK 1718/4885PPARA 726/4885
US-20240091205-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE APEH, UGT1A9, ALDH3A1 CTSS 503/4885CTSK 543/4885PPARA 4402/4885
US-11186541-B2 Potent inhibitors of aspartate N-acetyl-transferase for the treatment of Canavan disease GOT1, ACAT1, GOT2 CTSS 776/4885CTSK 927/4885PPARA 3673/4885
US-20200085794-A1 RILUZOLE PRODRUGS AND THEIR USE APEH, ALDH1A2, UGT1A9 CTSS 653/4885CTSK 586/4885PPARA 4317/4885
US-10639298-B2 Prodrugs of riluzole and their method of use APEH, UGT1A9, ALDH3A1 CTSS 503/4885CTSK 543/4885PPARA 4402/4885
US-20180147298-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS HDLBP, APOB, TSG101 CTSS 2817/4885CTSK 3216/4885PPARA 3086/4885
US-20210236470-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE APEH, UGT1A9, ALDH3A1 CTSS 503/4885CTSK 543/4885PPARA 4402/4885
US-20120232081-A1 CYCLIC (AZA)INDOLIZINECARBOXAMIDES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS REN, ACE, PM20D2 CTSS 462/4885CTSK 409/4885PPARA 3032/4885
US-20250025438-A1 Derivative of aspartic acid and use thereof in treatment of metabolic diseases such as hepatic fibrosis and non-alcoholic hepatitis GOT1, GOT2, GLS2 CTSS 958/4885CTSK 1138/4885PPARA 211/4885
US-20180028664-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS HDLBP, APOB, TSG101 CTSS 2817/4885CTSK 3216/4885PPARA 3086/4885
US-20210228549-A1 RILUZOLE PRODRUGS AND THEIR USE APEH, ALDH1A2, UGT1A9 CTSS 653/4885CTSK 586/4885PPARA 4317/4885
US-20230381149-A1 RILUZOLE PRODRUGS AND THEIR USE APEH, ALDH1A2, UGT1A9 CTSS 653/4885CTSK 586/4885PPARA 4317/4885
US-20220396555-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE APEH, UGT1A9, ALDH3A1 CTSS 503/4885CTSK 543/4885PPARA 4402/4885
US-20070154948-A1 Novel antibacterial agents ENGASE, PGLS, PEPD CTSS 348/4885CTSK 748/4885PPARA 3639/4885
US-20090111737-A1 Novel antibacterial agents ENGASE, PGLS, PEPD CTSS 348/4885CTSK 748/4885PPARA 3639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.