Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP1A1 | P05023 | 3/20 | 0.54 |
| ▸ | ATP1B1 | P05026 | 3/20 | 0.54 |
| ▸ | ATP1A3 | P13637 | 3/20 | 0.54 |
| ▸ | ATP1B2 | P14415 | 3/20 | 0.54 |
| ▸ | ATP1A2 | P50993 | 3/20 | 0.54 |
| ▸ | ATP1B3 | P54709 | 3/20 | 0.54 |
| ▸ | FXYD2 | P54710 | 3/20 | 0.54 |
| ▸ | ATP1A4 | Q13733 | 3/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 9/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | CDC25A | P30304 | 7/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4192628 | 1.00 | ATP1A1 (0.54) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL3121878 | 0.90 | DUSP3 (0.51) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL30568384 | 0.88 | ALOX15 (0.49) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL5444056 | 0.88 | ATP1A1 (0.50) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL5444054 | 0.88 | ATP1A1 (0.50) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL25669593 | 0.85 | ATP1A1 (0.48) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL25669572 | 0.85 | ATP1A1 (0.48) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL29934243 | 0.85 | DUSP3 (0.49) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL13455165 | 0.83 | DUSP3 (0.56) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL30236154 | 0.83 | DUSP3 (0.56) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2783004-B1 | DITERPENE SYNTHASES AND METHOD FOR PRODUCING DITERPENOIDS | UNIV BRITISH COLUMBIA (CA) | 2019-08-07 | — | — | EP | disclosed |
| US-20170321230-A1 | Diterpene Synthases and Method for Producing Diterpenoids | UNIV BRITISH COLUMBIA (CA) | 2017-11-09 | — | — | US | disclosed |
| US-9677091-B2 | Diterpene synthases and method for producing diterpenoids | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2017-06-13 | — | — | US | disclosed |
| EP-1837029-B2 | Composition for prevention and treatment of coughs and colds | PANDALIS GEORGIOS (DE) | 2016-09-21 | — | — | EP | disclosed |
| US-20150037854-A1 | DITERPENE SYNTHASES AND METHOD FOR PRODUCING DITERPENOIDS | UNIVERSITY OF BRITISH COLUMBIA (CA) | 2015-02-05 | — | — | US | disclosed |
| US-8889381-B2 | Diterpene synthases and method for producing diterpenoids | UNIVERSITY OF BRITISH COLUMBIA (CA) | 2014-11-18 | — | — | US | disclosed |
| EP-2783004-A1 | DITERPENE SYNTHASES AND METHOD FOR PRODUCING DITERPENOIDS | The University of British Columbia (CA) | 2014-10-01 | — | — | EP | disclosed |
| US-20130224809-A1 | Diterpene Synthases And Method For Producing Diterpenoids | UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-08-29 | — | — | US | disclosed |
| WO-2013075239-A1 | DITERPENE SYNTHASES AND METHOD FOR PRODUCING DITERPENOIDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-05-30 | — | — | WO | disclosed |
| US-20090061027-A1 | Composition For The Prevention and Treatment Of Common Cold Diseases | PANDALIS GEORGIOS | 2009-03-05 | — | — | US | disclosed |
| EP-1837029-B1 | Composition for prevention and treatment of coughs and colds | PANDALIS GEORGIOS (DE) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007110133-A1 | COMPOSITION FOR THE PREVENTION AND TREATMENT OF COMMON COLD DISEASES | PANDALIS GEORGIOS (DE) | 2007-10-04 | — | — | WO | disclosed |
| EP-1837029-A1 | Composition for prevention and treatment of coughs and colds | Pandalis, Georgios (DE) | 2007-09-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170321230-A1 | Diterpene Synthases and Method for Producing Diterpenoids | DHPS, GGPS1, FDPS | ATP1A1 3237/4885ATP1B1 3001/4885ATP1A3 3904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.