SCHEMBL4185847

SCHEMBL4185847

CC(CC1CCCCC1)NCc1ccccc1NC(=O)Nc1ccc(Cl)c(Cl)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.47
MEN1 O00255 5/20 0.47
MAPT P10636 5/20 0.47
NPC1 O15118 5/20 0.47
RAB9A P51151 5/20 0.47
POLB P06746 2/20 0.47
GAA P10253 1/20 0.47
KDM4E B2RXH2 3/20 0.46
ALDH1A1 P00352 3/20 0.46
NFKB1 P19838 1/20 0.46
GFER P55789 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MAPK14 Q16539 1/20 0.45
TRPV1 Q8NER1 4/20 0.43
EPHX1 P07099 1/20 0.42
EPHX2 P34913 1/20 0.42
MAPK1 P28482 1/20 0.41
IDO1 P14902 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4193462 0.91 TAS1R3 (0.44) KMT2AMEN1NPC1RAB9AKDM4E
SCHEMBL4195012 0.89 SMN1; SMN2 (0.47) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL4196799 0.87 CCR3 (0.50) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL4202587 0.85 RAB9A (0.47) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL4193564 0.85 HTT (0.56) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL4202574 0.84 RAB9A (0.46) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL4191213 0.83 CCR3 (0.55) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL4197445 0.82 KMT2A (0.48) KMT2AMEN1POLBALDH1A1SMN1; SMN2
SCHEMBL4196629 0.82 KMT2A (0.48) KMT2AMEN1POLBALDH1A1SMN1; SMN2
SCHEMBL4195095 0.82 KMT2A (0.48) KMT2AMEN1POLBALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP claimed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US claimed
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP disclosed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US disclosed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215764-A1 Antimicrobial agents TUFM, RPS17, HARS1 KMT2A 2047/4885MEN1 3776/4885MAPT 2269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.