SCHEMBL419372

SCHEMBL419372

Cc1cccc(COc2ccc(S(=O)(=O)c3ccc(O)cc3)cc2)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.60
GAA P10253 1/20 0.50
PKM P14618 1/20 0.50
HTT P42858 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
MAOA P21397 1/20 0.50
FFAR1 O14842 3/20 0.49
LMNA P02545 1/20 0.49
CYP1A2 P05177 1/20 0.49
PTGS1 P23219 1/20 0.49
SLC6A2 P23975 1/20 0.49
CYP2C19 P33261 1/20 0.49
PTGS2 P35354 1/20 0.49
SLC6A3 Q01959 1/20 0.49
HIF1A Q16665 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
MMP1 P03956 1/20 0.48
ADAM17 P78536 1/20 0.48
NR1H4 Q96RI1 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51406 0.90 LMNA (0.56) GAAPKMFFAR1LMNACYP1A2
SCHEMBL10866245 0.88 MAOB (0.69) MAOBMAOAFFAR1LMNACYP1A2
SCHEMBL420238 0.82 MAOB (0.56) MAOBGAAPKMHTTLMNA
SCHEMBL419556 0.82 LMNA (0.73) MAOBGAAPKML3MBTL1LMNA
SCHEMBL9788125 0.80 RAPGEF4 (0.56) GAAPKMHTTTDP1L3MBTL1
SCHEMBL6280745 0.80 GAA (0.59) GAAPKMLMNACYP1A2PTGS1
SCHEMBL51564 0.80 GAA (0.59) GAAPKMLMNACYP1A2PTGS1
SCHEMBL8982841 0.80 CYP1A2 (0.45) GAAPKML3MBTL1FFAR1LMNA
SCHEMBL257781 0.78 MAOB (0.69) MAOBMAOAFFAR1
SCHEMBL9661811 0.78 CA12 (0.57) MAOBFFAR1LMNACYP1A2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140004071-A1 Thermochromic Dental Material BROWN WILLIAM STEVEN (US) 2014-01-02 US claimed
EP-0997315-A1 Polycyclic phenol compounds and heat-sensitive recording materials employing them Nicca Chemical Co., Ltd. (JP) 2000-05-03 EP claimed
US-12030328-B2 Thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2024-07-09 US disclosed
WO-2023153481-A1 THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2023-08-17 WO disclosed
EP-4227107-A1 THERMOSENSITIVE RECORDING MEDIUM Ricoh Company, Ltd. (JP) 2023-08-16 EP disclosed
US-20230147446-A1 THERMOSENSITIVE RECORDING MEDIUM AND METHOD FOR PRODUCING THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2023-05-11 US disclosed
EP-4126557-A1 THERMOSENSITIVE RECORDING MEDIUM AND METHOD FOR PRODUCING THERMOSENSITIVE RECORDING MEDIUM Ricoh Company, Ltd. (JP) 2023-02-08 EP disclosed
US-20220153052-A1 THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2022-05-19 US disclosed
EP-3941756-A1 THERMOSENSITIVE RECORDING MEDIUM Ricoh Company, Ltd. (JP) 2022-01-26 EP disclosed
US-11046043-B2 Linerless thermosensitive recording body package RICOH COMPANY, LTD. (JP) 2021-06-29 US disclosed
CN-109328143-B Thermosensitive recording medium and article 株式会社理光 2021-03-23 CN disclosed
EP-1816003-A1 Thermosensitive recording material and method for producing the same Ricoh Company, Ltd. (JP) 2007-08-08 EP disclosed
US-20060216537-A1 Coating paper which can be removed by water and a method for preparation thereof NIPPON PAPER PAPYLIA CO., LTD. (JP) 2006-09-28 US disclosed
EP-1705288-A2 A coating paper which can be removed by water and a method for preparation thereof Nippon Paper Industries Co., Ltd. (JP) 2006-09-27 EP disclosed
JP-2000136180-A POLYCYCLIC PHENOL COMPOUND AND HEAT-SENSITIVE RECORDING MATERIAL USING THE SAME NICCA CHEMICAL CO LTD 2000-05-16 JP disclosed
EP-0997315-A1 Polycyclic phenol compounds and heat-sensitive recording materials employing them Nicca Chemical Co., Ltd. (JP) 2000-05-03 EP disclosed
US-5102693-A Calendering intermediate layer to smooth surface, coating onto support and forming a thermosensitive coloring layer RICOH COMPANY, LTD. (JP) 1992-04-07 US disclosed
US-4975408-A INTERMEDIATE INSULATING LAYER HAVING SURFACE SMOOTHNESS GIVING IMPROVED COLORING SENSITIVITY; FOAMED LAYER HAVING MINUTE VOIDS RICOH COMPANY, LTD. (JP) 1990-12-04 US disclosed
US-4912079-A Thermosensitive coloring layer RICOH COMPANY, LTD. (JP) 1990-03-27 US disclosed
US-4895828-A INTERMEDIATE EXPANDED PLASTIC FILLER LAYER AND ELECTROCONDUCTIVE MATERIAL RICOH COMPANY, LTD. (JP) 1990-01-23 US disclosed