SCHEMBL4194028

SCHEMBL4194028

CC(CC1CCCCC1)NCc1ncccc1NS(=O)(=O)c1ccc(-n2cncn2)c(F)c1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
SCN9A Q15858 2/20 0.35
GLO1 Q04760 1/20 0.35
MOGAT2 Q3SYC2 10/20 0.34
ACLY P53396 1/20 0.34
GPR119 Q8TDV5 1/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4185999 0.89 KDM4E (0.40) CYP1A2CYP3A4CYP2C9CYP2C19SCN9A
SCHEMBL4203965 0.88 KDM4E (0.39) CYP1A2CYP3A4CYP2C9CYP2C19MOGAT2
SCHEMBL4194889 0.79 ACLY (0.47) SCN9AMOGAT2ACLYMEN1KMT2A
SCHEMBL4184085 0.79 ACLY (0.47) SCN9AMOGAT2ACLYMEN1KMT2A
SCHEMBL4706166 0.78 GLO1 (0.35) SCN9AGLO1MOGAT2MEN1KMT2A
SCHEMBL4193413 0.78 ACLY (0.48) MOGAT2ACLYMEN1KMT2A
SCHEMBL4190554 0.76 KDM4E (0.40) SCN9AMOGAT2
SCHEMBL4201552 0.76 KDM4E (0.40) CYP3A4CYP2C9CYP2C19SCN9AMOGAT2
SCHEMBL4198310 0.76 KDM4E (0.44) ACLYMEN1KMT2A
SCHEMBL4184025 0.75 KDM4E (0.39) CYP3A4CYP2C9CYP2C19SCN9AMOGAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP claimed
CN-101203504-B Antimicrobial agents RANBAXY LAB LTD 2012-11-14 CN claimed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US claimed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US claimed
CN-101203504-A Antimicrobial agents RANBAXY LAB LTD (IN) 2008-06-18 CN claimed
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP disclosed
CN-101203504-B Antimicrobial agents RANBAXY LAB LTD 2012-11-14 CN disclosed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US disclosed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US disclosed
CN-101203504-A Antimicrobial agents RANBAXY LAB LTD (IN) 2008-06-18 CN disclosed
EP-1879877-A2 ANTIMICROBIAL AGENTS Ranbaxy Laboratories Limited (IN) 2008-01-23 EP disclosed
WO-2006117762-A2 ANTIMICROBIAL AGENTS RANBAXY LABORATORIES LIMITED (IN) 2006-11-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215764-A1 Antimicrobial agents TUFM, RPS17, HARS1 CYP1A2 2765/4885CYP3A4 1763/4885CYP2C9 3172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.