SCHEMBL4195595

SCHEMBL4195595

C[C@@H](CC1CCCCCC1)NCc1ccccc1NS(=O)(=O)c1ccc(-c2ccon2)s1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
PFKFB3 Q16875 1/20 0.41
MMP8 P22894 4/20 0.37
MMP3 P08254 2/20 0.37
KDM4E B2RXH2 1/20 0.37
PKM P14618 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
F10 P00742 4/20 0.36
F2 P00734 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
POLB P06746 3/20 0.35
ALDH1A1 P00352 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAPT P10636 3/20 0.34
TP53 P04637 2/20 0.34
NR1H2 P55055 1/20 0.33
PTGES2 Q9H7Z7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4184130 1.00 KMT2A (0.41) KMT2AMEN1PFKFB3MMP8MMP3
SCHEMBL4195547 0.99 KMT2A (0.42) KMT2AMEN1PFKFB3MMP8MMP3
SCHEMBL4197648 0.87 KMT2A (0.40) KMT2AMEN1PFKFB3MMP8MMP3
SCHEMBL4185970 0.86 KDM4E (0.40) KMT2AMEN1PFKFB3KDM4EPKM
SCHEMBL4200017 0.86 MAPT (0.52) KDM4EPKMRXFP1NPC1RAB9A
SCHEMBL4197588 0.86 MAPT (0.52) KDM4EPKMRXFP1NPC1RAB9A
SCHEMBL4186012 0.85 KDM4E (0.38) KDM4EPKMRXFP1NPC1RAB9A
SCHEMBL4201621 0.85 KDM4E (0.38) KDM4EPKMRXFP1NPC1RAB9A
SCHEMBL4197533 0.85 PKM (0.36) KMT2AMEN1KDM4EPKMRXFP1
SCHEMBL4197564 0.85 KDM4E (0.39) KMT2AMEN1PFKFB3MMP3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP claimed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US claimed
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP disclosed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US disclosed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215764-A1 Antimicrobial agents TUFM, RPS17, HARS1 KMT2A 2047/4885MEN1 3776/4885PFKFB3 2039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.