SCHEMBL4196236

SCHEMBL4196236

O=C(Nc1ccccc1)NS(=O)(=O)c1ccccc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.78
CYP2C9 P11712 1/20 0.71
ACP1 P24666 2/20 0.67
CA12 O43570 5/20 0.60
CA1 P00915 5/20 0.60
CA2 P00918 5/20 0.60
CA9 Q16790 5/20 0.60
TP53 P04637 2/20 0.59
EPHX1 P07099 1/20 0.59
TSHR P16473 1/20 0.59
EPHX2 P34913 1/20 0.59
CDK9 P50750 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
CLK4 Q9HAZ1 1/20 0.59
MAPT P10636 1/20 0.56
CA4 P22748 1/20 0.55
CA6 P23280 1/20 0.55
CA5A P35218 1/20 0.55
CA7 P43166 1/20 0.55
CA13 Q8N1Q1 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6297294 0.93 LMNA (0.79) LMNACYP2C9ACP1CA12CA1
SCHEMBL9485882 0.88 MAOA (0.64) LMNACYP2C9ACP1CA12CA1
SCHEMBL4457678 0.88 TP53 (0.73) LMNACYP2C9ACP1CA12CA1
SCHEMBL7276663 0.88 LMNA (0.63) LMNACYP2C9ACP1CA12CA1
SCHEMBL9529388 0.88 LMNA (0.63) LMNACYP2C9ACP1CA12CA1
SCHEMBL23486695 0.88 LMNA (0.88) LMNACYP2C9CA12CA1CA2
SCHEMBL5186566 0.88 LMNA (0.72) LMNACYP2C9ACP1CA12CA1
SCHEMBL6295746 0.88 CA12 (0.69) LMNACYP2C9ACP1CA12CA1
SCHEMBL27885 0.88 LMNA (1.00) LMNACYP2C9ACP1CA12CA1
SCHEMBL6301443 0.87 LMNA (0.70) LMNACYP2C9ACP1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1448397-B1 HEAT-SENSITIVE RECORDING MATERIAL JUJO THERMAL OY (FI) 2007-07-11 EP claimed
US-20050148467-A1 Heat-sensitive recording material JUJO THERMAL OY (FI) 2005-07-07 US claimed
EP-1448397-A1 HEAT-SENSITIVE RECORDING MATERIAL Jujo Thermal Oy (FI) 2004-08-25 EP claimed
WO-2003031194-A1 HEAT-SENSITIVE RECORDING MATERIAL JUJO THERMAL OY (FI) 2003-04-17 WO claimed
EP-0610653-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1997-04-16 EP claimed
EP-0512560-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1996-03-20 EP claimed
EP-0620122-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1996-03-13 EP claimed
EP-0526072-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-09-13 EP claimed
US-5446010-A Substrate sheet, thermosensitive colored image forming layer containing colorless dye precursor, binder, color developing agent having sulfonylureido group, aromatic amide sensitizer; storage stability NEW OJI PAPER CO., LTD. (JP) 1995-08-29 US claimed
US-5444036-A Arylsulfonylureido compound, acetoacetanilide compound, sulfonamide derivative; storage stability NEW OIL PAPER CO., LTD. (JP) 1995-08-22 US claimed
EP-0542556-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-07-19 EP claimed
EP-0620122-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-10-19 EP claimed
EP-0610653-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-08-17 EP claimed
US-5314859-A Thermosensitive recording material OJI PAPER CO., LTD. (JP) 1994-05-24 US claimed
US-5292711-A Thermosensitive recording material OJI PAPER CO., LTD. (JP) 1994-03-08 US claimed
US-5246906-A Sulfonyl-urea or -thiourea color developer, oil and plasticizer resistant, storage stable OJI PAPER CO., LTD. (JP) 1993-09-21 US claimed
EP-0542556-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-05-19 EP claimed
EP-0526072-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-02-03 EP claimed
EP-0512560-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1992-11-11 EP claimed
US-4072712-A FROM ISOCYANATES, CATALYSIS BAYER AKTIENGESELLSCHAFT (DT) 1978-02-07 US claimed