SCHEMBL6301443

SCHEMBL6301443

O=C(Nc1ccccc1)NS(=O)(=O)c1ccc(NC(=S)Nc2ccccc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.70
CYP2C9 P11712 1/20 0.65
PTPN7 P35236 1/20 0.62
ALDH1A1 P00352 4/20 0.61
MAPT P10636 2/20 0.59
PTGS2 P35354 1/20 0.59
ACP1 P24666 2/20 0.56
CA12 O43570 2/20 0.55
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
CA9 Q16790 2/20 0.55
TP53 P04637 1/20 0.55
CA4 P22748 1/20 0.55
CA6 P23280 1/20 0.55
CA5A P35218 1/20 0.55
CA7 P43166 1/20 0.55
CA13 Q8N1Q1 1/20 0.55
CA14 Q9ULX7 1/20 0.55
SMN1; SMN2 Q16637 2/20 0.54
GAA P10253 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6297294 0.90 LMNA (0.79) LMNACYP2C9ALDH1A1MAPTACP1
SCHEMBL4196236 0.87 LMNA (0.78) LMNACYP2C9MAPTACP1CA12
SCHEMBL6301527 0.87 MAPT (0.58) LMNACYP2C9PTPN7ALDH1A1MAPT
SCHEMBL6295729 0.85 MEN1 (0.61) LMNAPTPN7ALDH1A1MAPTCA1
SCHEMBL5186566 0.83 LMNA (0.72) LMNACYP2C9ALDH1A1MAPTACP1
SCHEMBL27885 0.83 LMNA (1.00) LMNACYP2C9ALDH1A1ACP1CA12
SCHEMBL4457678 0.83 TP53 (0.73) LMNACYP2C9ACP1CA12CA1
SCHEMBL3396831 0.82 ALDH1A1 (0.85) LMNAPTPN7ALDH1A1MAPTSMN1; SMN2
SCHEMBL6297115 0.81 ACP1 (0.51) LMNACYP2C9PTPN7ALDH1A1MAPT
SCHEMBL7774811 0.80 GAA (0.62) LMNACYP2C9PTPN7ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6921740-B1 Electron-receiving compound and thermal recording material MITSUBISHI PAPER MIILS LTD. (JP) 2005-07-26 US disclosed