SCHEMBL41971

SCHEMBL41971

FC(F)(F)Oc1cc[c]cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.42
EPHX2 P34913 1/20 0.42
NISCH Q9Y2I1 1/20 0.40
ALDH1A1 P00352 2/20 0.39
TSHR P16473 2/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
BLM P54132 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HIF1A Q16665 1/20 0.39
HSD17B10 Q99714 1/20 0.39
EPAS1 Q99814 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
GPR3 P46089 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.37
KDM4E B2RXH2 1/20 0.37
KIF11 P52732 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28109965 0.97 GPR3 (0.42) MAPTEPHX2NISCHALDH1A1TSHR
SCHEMBL28513358 0.97 MAPT (0.41) MAPTEPHX2NISCHALDH1A1TSHR
SCHEMBL28046390 0.97 MAPT (0.41) MAPTEPHX2NISCHALDH1A1TSHR
SCHEMBL28175586 0.93 MAPT (0.42) MAPTEPHX2NISCHALDH1A1TSHR
SCHEMBL29154791 0.91 MAPT (0.37) MAPTEPHX2NISCHALDH1A1TSHR
SCHEMBL920510 0.91 EPHX2 (0.42) MAPTEPHX2NISCHALDH1A1TSHR
SCHEMBL533257 0.86 KIF11 (0.47) MAPTEPHX2NISCHKIF11NOTUM
SCHEMBL6573034 0.86 KIF11 (0.47) MAPTEPHX2NISCHKIF11NOTUM
SCHEMBL9325490 0.82
SCHEMBL16791890 0.81 ALDH1A1 (0.35) MAPTALDH1A1TSHRKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13214 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290406-A Method for synthesizing tetrahydrofuran compound by organic catalysis 中国海洋大学 2024-07-05 CN claimed
WO-2024140294-A1 ORGANIC COMPOUND AND APPLICATION THEREOF IN OLED DEVICE 北京云基科技股份有限公司 2024-07-04 WO claimed
EP-4392419-A1 NOVEL PYRAZINYL-TRIAZOLE COMPOUNDS AS PESTICIDES Bayer Aktiengesellschaft (DE) 2024-07-03 EP claimed
CN-118265702-A Microbiocidal isonicotinamide derivatives 先正达农作物保护股份公司 2024-06-28 CN claimed
US-20240208902-A1 CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2024-06-27 US claimed
CN-118241228-A Preparation method of alpha- (hetero) aryl ether compound 青岛科技大学 2024-06-25 CN claimed
CN-118215662-A Modulators of CCR6 receptors 爱杜西亚药品有限公司 2024-06-18 CN claimed
CN-114621209-B 1,2, 3-Thiadiazole acetonitrile derivatives, and preparation method and application thereof 南开大学 2024-06-14 CN claimed
EP-3849664-B1 PHENOXY-PYRIDYL-PYRIMIDINE COMPOUNDS AND METHODS OF USE GENENTECH INC (US) 2024-06-12 EP claimed
CN-115010915-B Nitrogen-branched nine-arm polyethylene glycol derivative, preparation method and modified biologically-relevant substance thereof 厦门赛诺邦格生物科技股份有限公司 2024-06-11 CN claimed
US-4115448-A Carbamylguanidine antimicrobial compounds COOPER LABORATORIES, INC. (US) 1978-09-19 US claimed
US-4110099-A INHIBITOR FOR INTERNODEL GROWTH OF PLANTS ELI LILLY AND COMPANY (US) 1978-08-29 US claimed
US-4110328-A Bis-carbamylguanidinoazaalkane antimicrobial compounds COOPER LABORATORIES, INC. (US) 1978-08-29 US claimed
US-4043791-A Method of regulating the growth of aquatic weeds with pyridine derivatives ELI LILLY AND COMPANY (US) 1977-08-23 US claimed
US-RE29367-E HERBICIDES, FUNGICIDES, 5-PYRIMIDINYL ELI LILLY AND COMPANY (US) 1977-08-23 US claimed
US-4022962-A DENTAL PLAQUE INHIBITORS COOPER LABORATORIES, INC. (US) 1977-05-10 US claimed
US-4017623-A Esters of 2-[(4-quinolyl)amino]-benzoic acids in analgesic and anti-inflammatory compositions SYNTHELABO (FR) 1977-04-12 US claimed
US-4002628-A HERBICIDES, PLANT FUNGICIDES, PLANT GROWTH REGULATORS ELI LILLY AND COMPANY (US) 1977-01-11 US claimed
US-3967949-A Fluoroalkoxyphenyl-substituted nitrogen heterocycles as plant stunting agents ELI LILLY AND COMPANY (US) 1976-07-06 US claimed
US-3935229-A ANALGESIC, ANTIINFLAMMATORY SYNTHELABO (FR) 1976-01-27 US claimed