Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 3/20 | 0.48 |
| ▸ | FLT4 | P35916 | 3/20 | 0.48 |
| ▸ | KDR | P35968 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11849847 | 0.91 | SMN1; SMN2 (0.55) | SMN1; SMN2RAB9ANPC1TSHRCASP1 | |
| SCHEMBL6941354 | 0.87 | TP53 (0.50) | PPARGPPARASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL5174489 | 0.84 | CYP3A4 (0.50) | PPARGPPARASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10395930 | 0.84 | RECQL (0.62) | PPARGPPARASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL21550127 | 0.82 | SMN1; SMN2 (0.50) | PPARGPPARASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL23070442 | 0.82 | HPGD (0.53) | SMN1; SMN2RAB9ANPC1TP53MAPT | |
| SCHEMBL1502321 | 0.82 | ALDH1A1 (0.48) | SMN1; SMN2RAB9ANPC1TP53TSHR | |
| SCHEMBL30185351 | 0.82 | SMN1; SMN2 (0.71) | PPARGSMN1; SMN2RAB9ATP53TSHR | |
| SCHEMBL195020 | 0.82 | SMN1; SMN2 (0.71) | PPARGSMN1; SMN2RAB9ATP53TSHR | |
| SCHEMBL9862051 | 0.82 | MEN1 (0.57) | SMN1; SMN2NPC1TSHRMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027307-A2 | PROCESS FOR PREPARING POROUS METAL ORGANIC FRAMEWORKS | BASF SE (DE) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007131948-A2 | PROCESS FOR PREPARING POROUS METAL ORGANIC FRAMEWORKS | BASF SE (DE) | 2007-11-22 | — | — | WO | disclosed |