SCHEMBL6941354

SCHEMBL6941354

Cc1ccc(C)c(C(=O)c2cc(Cl)ccc2Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.50
ALDH1A1 P00352 2/20 0.50
RAB9A P51151 2/20 0.46
NPC1 O15118 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
RECQL P46063 1/20 0.45
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
S1PR4 O95977 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
ABCB1 P08183 1/20 0.42
LMNA P02545 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
ANO1 Q5XXA6 1/20 0.41
ERCC5 P28715 1/20 0.41
FEN1 P39748 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11851362 0.93 ALDH1A1 (0.57) TP53ALDH1A1RAB9ANPC1SMN1; SMN2
SCHEMBL4197290 0.87 PPARG (0.54) TP53ALDH1A1RAB9ANPC1SMN1; SMN2
SCHEMBL1502321 0.86 ALDH1A1 (0.48) TP53ALDH1A1RAB9ANPC1SMN1; SMN2
SCHEMBL8160214 0.82 ALDH1A1 (0.71) TP53ALDH1A1RAB9ASMN1; SMN2RECQL
SCHEMBL9862051 0.82 MEN1 (0.57) ALDH1A1NPC1SMN1; SMN2MEN1KMT2A
SCHEMBL9717031 0.81 ABCB1 (0.56) ALDH1A1RAB9ASMN1; SMN2RECQLMEN1
SCHEMBL11851691 0.81 ALDH1A1 (0.52) TP53ALDH1A1RAB9ASMN1; SMN2RECQL
SCHEMBL6940121 0.81 RECQL (0.58) TP53ALDH1A1SMN1; SMN2RECQLMEN1
SCHEMBL8197244 0.81 RECQL (0.68) TP53ALDH1A1RECQLMEN1KMT2A
SCHEMBL11849847 0.81 SMN1; SMN2 (0.55) ALDH1A1RAB9ANPC1SMN1; SMN2RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1352731-A2 Method of orienting polymer molecules MISSISSIPPI POLYMER TECHNOLOGIES, INC. (US) 2003-10-15 EP disclosed
EP-0629217-B1 RIGID-ROD POLYMERS MISSISSIPPI POLYMER TECHNOLOGI (US) 2003-05-07 EP disclosed
US-6087467-A POLY-P-PHENYLENE AND SOLUBLE ORGANIC GROUPS MAXDEM INCORPORATED (US) 2000-07-11 US disclosed
US-5976437-A POLYPHENYL RESINS WITH PENDANT SOLUBILIZING GROUPS; MELT, WET, AND DRY-JET WET SPINNING; ORIENTING BY DRAWING OR STRETCHING; COATING SOLID ARTICLES MAXDEM INCORPORATED (US) 1999-11-02 US disclosed
US-5789521-A POLYPHENYL RESINS MAXDEM INCORPORATED (US) 1998-08-04 US disclosed
US-5760131-A IMPROVING THE FIRE RESISTANCE BY BLENDING WITH A POLYPHENYL RESINS MAXDEM INCORPORATED (US) 1998-06-02 US disclosed
US-5756581-A Rigid-rod polymers MAXDEM INCORPORATED (US) 1998-05-26 US disclosed
US-5731400-A FABRICATING FREE STANDING FILM OF SOLUBLE RIGID ROD POLYETHER SUBSTITUTED WITH SOLUBILIZING SIDE GROUP BY MELTING POLYMER AND EXTRUDING THROUGH SLIT MAXDEM INCORPORATED (US) 1998-03-24 US disclosed
US-5721335-A COMPRESSION MOLDING A POLYPHENYL RESIN HOMO- OR COPOLYMER; MELT PROCESSABILITY MAXDEM INCORPORATED (US) 1998-02-24 US disclosed
US-5654392-A POLYPHENYL RESINS HAVING SOLUBILIZING SIDE GROUPS MAXDEM INCORPORATED (US) 1997-08-05 US disclosed
US-5646231-A POLYPHENYL RESINS MAXDEM, INCORPORATED (US) 1997-07-08 US disclosed
US-5646232-A MANUFACTURING POLYPHENYL RESINS MAXDEM INCORPORATED (US) 1997-07-08 US disclosed