SCHEMBL419839

SCHEMBL419839

N=C(N)c1ccc(-c2cc3ccccc3[nH]2)c(C(=N)N)c1

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
F2 P00734 14/20 0.59
F10 P00742 12/20 0.59
PLG P00747 12/20 0.59
PLAU P00749 12/20 0.59
PRSS1 P07477 12/20 0.59
PLAT P00750 9/20 0.59
HPN P05981 3/20 0.59
PRSS2 P07478 3/20 0.59
PRSS3 P35030 3/20 0.59
ST14 Q9Y5Y6 2/20 0.59
KLKB1 P03952 1/20 0.53
F7 P08709 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29429330 1.00 F2 (0.59) F2F10PLGPLAUPRSS1
Hydrochloric Acid SCHEMBL1256806 0.99 F2 (0.58) F2F10PLGPLAUPRSS1
Hydrochloric Acid SCHEMBL29614824 0.99 F2 (0.58) F2F10PLGPLAUPRSS1
Hydrochloric Acid SCHEMBL29692564 0.99 F2 (0.58) F2F10PLGPLAUPRSS1
Hydrochloric Acid SCHEMBL688900 0.99 F2 (0.58) F2F10PLGPLAUPRSS1
Hydrochloric Acid SCHEMBL4259347 0.97 F2 (0.56) F2F10PLGPLAUPRSS1
SCHEMBL2874094 0.83 F2 (0.59) F2F10PLGPLAUPRSS1
SCHEMBL29493199 0.79 F2 (0.70) F2F10PLGPLAUPRSS1
SCHEMBL2864097 0.77 PLAU (0.52) F2F10PLGPLAUPRSS1
SCHEMBL4995709 0.74 F2 (1.00) F2F10PLGPLAUPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4158064-A1 DEVICES AND METHODS FOR GENOMIC ANALYSIS Dimensiongen (KY) 2023-04-05 EP claimed
US-11299519-B2 Host cells and methods using a repressor polypeptide and an inducible promoter for gene expression THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-04-12 US claimed
CN-112313495-A Sample preparation for antimicrobial susceptibility testing 赛录科试诊断公司 2021-02-02 CN claimed
EP-3759461-A1 SAMPLE PREPARATION FOR ANTIMICROBIAL SUSCEPTIBILITY TESTING Selux Diagnostics, Inc. (US) 2021-01-06 EP claimed
US-20200262875-A1 Host cells and methods using a repressor polypeptide and an inducible promoter for gene expression THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-08-20 US claimed
EP-3380840-B1 METHODS OF PREDICTING PROGRESSION OF BARRETT'S ESOPHAGUS CERNOSTICS INC (US) 2020-08-19 EP claimed
US-20150185150-A1 METHOD FOR NORMALIZING THE LUMINESCENCE EMITTED BY A MEASURING MEDIUM CISBIO BIOASSAYS (FR) 2015-07-02 US claimed
EP-2817614-A1 METHOD FOR NORMALISING THE LUMINESCENCE EMITTED BY A MEASURING MEDIUM Cisbio Bioassays (FR) 2014-12-31 EP claimed
WO-2013124544-A1 METHOD FOR NORMALISING THE LUMINESCENCE EMITTED BY A MEASURING MEDIUM CISBIO BIOASSAYS (FR) 2013-08-29 WO claimed
US-7683170-B2 Methods for preparing Irinotecan W. C. HERAEUS GMBH (DE) 2010-03-23 US claimed
WO-2009058997-A2 NON-INVASIVE ISOLATION OF FETAL NUCLEIC ACID BIOCEPT INC. (US) 2009-05-07 WO claimed
EP-0443823-B1 Quantitative determination of a DNA polymerase and a test kit useful in same JOHNSON & JOHNSON CLIN DIAG (US) 1995-11-08 EP claimed
US-5049490-A Quantitative determination of a DNA polymerase and a test kit useful in same EASTMAN KODAK CO. (US) 1991-09-17 US claimed
EP-0443823-A1 Quantitative determination of a DNA polymerase and a test kit useful in same Johnson & Johnson Clinical Diagnostics, Inc. (US) 1991-08-28 EP claimed
US-20260130659-A1 EXTRACELLULAR MATRIX (ECM) HYDROGEL AS A SUBMUCOSAL FLUID CUSHION UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2026-05-14 US disclosed
US-12622896-B2 Antiviral compounds, compositions and methods of use THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2026-05-12 US disclosed
US-20260125678-A1 DNA IMMORTALIZATION CONSTRUCT AND PERFORMING PRIMARY CELL IMMORTALIZATION GOVERNMENT OF THE US SECRETARY OF COMMERCE (US) 2026-05-07 US disclosed
US-5049490-A Quantitative determination of a DNA polymerase and a test kit useful in same EASTMAN KODAK CO. (US) 1991-09-17 US disclosed
EP-0443823-A1 Quantitative determination of a DNA polymerase and a test kit useful in same Johnson & Johnson Clinical Diagnostics, Inc. (US) 1991-08-28 EP disclosed
EP-0289908-A2 Microorganisms and methods for degrading plant cell walls and complex hydrocarbons THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1988-11-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125678-A1 DNA IMMORTALIZATION CONSTRUCT AND PERFORMING PRIMARY CELL IMMORTALIZATION MYC, TERT, POT1 F2 2563/4885F10 2132/4885PLG 3609/4885
US-20260130659-A1 EXTRACELLULAR MATRIX (ECM) HYDROGEL AS A SUBMUCOSAL FLUID CUSHION MMP1, SERPINE1, ADAMTS5 F2 626/4885F10 1272/4885PLG 43/4885
US-12622896-B2 Antiviral compounds, compositions and methods of use SARS1, NSUN2, ZC3HAV1 F2 2900/4885F10 3888/4885PLG 4701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.