Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13359408 | 0.87 | APP (0.38) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL35763 | 0.79 | PTGS1 (0.35) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL1078938 | 0.79 | PTGS1 (0.35) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL4883135 | 0.78 | PTGS1 (0.38) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL23242898 | 0.77 | PTGS1 (0.33) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL29538945 | 0.77 | CYP2D6 (0.35) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL4736677 | 0.76 | PTGS1 (0.32) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| Water SCHEMBL8593341 | 0.76 | PTGS1 (0.32) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL439388 | 0.74 | PTGS1 (0.35) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL8553870 | 0.72 | CYP2D6 (0.33) | PTGS1PDE4ALMNASLC6A6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090312539-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF CARBAPENEM ANTIBIOTIC | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2009-12-17 | — | — | US | disclosed |
| WO-2008062279-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF CARBAPENEM ANTIBIOTIC | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312539-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF CARBAPENEM ANTIBIOTIC | MGAM, TREH, ABCB11 | PTGS1 4210/4885PDE4A 3177/4885LMNA 554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.