Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL918122 | 0.88 | APP (0.37) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL918752 | 0.79 | LMNA (0.36) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL24451378 | 0.79 | ALDH1A1 (0.37) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL439388 | 0.77 | PTGS1 (0.35) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL4404059 | 0.77 | LMNA (0.35) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL35763 | 0.77 | PTGS1 (0.35) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL1078938 | 0.77 | PTGS1 (0.35) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL12927516 | 0.76 | HTT (0.35) | DPP4HTT | |
| SCHEMBL29538945 | 0.76 | CYP2D6 (0.35) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL23242898 | 0.76 | PTGS1 (0.33) | PTGS1PDE4ALMNASLC6A6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170313920-A1 | Biological Buffers with Wide Buffering Ranges | DALY THOMAS P (US) | 2017-11-02 | — | — | US | disclosed |
| US-20170260435-A1 | Biological Buffers with Wide Buffering Ranges | DALY THOMAS P (US) | 2017-09-14 | — | — | US | disclosed |
| US-20160369142-A1 | Biological Buffers with Wide Buffering Ranges | DALY THOMAS P (US) | 2016-12-22 | — | — | US | disclosed |
| US-9475754-B2 | Biological buffers with wide buffering ranges | TPAT IP LLC | 2016-10-25 | — | — | US | disclosed |
| US-20160280634-A1 | Biological Buffers with Wide Buffering Ranges | TPAT IP LLC | 2016-09-29 | — | — | US | disclosed |
| US-9447310-B2 | Biological buffers with wide buffering ranges | TPAT IP LLC | 2016-09-20 | — | — | US | disclosed |
| US-20160194283-A1 | Biological Buffers with Wide Buffering Ranges | TPAT IP LLC | 2016-07-07 | — | — | US | disclosed |
| US-9090638-B2 | Biological buffers with wide buffering ranges | TPAT IP LLC | 2015-07-28 | — | — | US | disclosed |
| US-8822728-B2 | Biological buffers with wide buffering ranges | TPAT IP LLC | 2014-09-02 | — | — | US | disclosed |
| US-20140073789-A1 | Biological Buffers with Wide Buffering Ranges | TPAT IP LLC | 2014-03-13 | — | — | US | disclosed |
| US-8519141-B2 | Biological buffers with wide buffering ranges | TPAT IP LLC | 2013-08-27 | — | — | US | disclosed |
| WO-2008070368-A2 | METHODS AND COMPOSITIONS FOR SKIN CARE | LIVING PROOF, INC. (US) | 2008-06-12 | — | — | WO | disclosed |
| EP-1446090-A2 | COMPOSITIONS CONTAINING ENZYMES STABILIZED WITH CERTAIN OSMO-PROTECTANTS AND METHODS FOR USING SUCH COMPOSITIONS IN PERSONAL CARE | THE PROCTER & GAMBLE COMPANY (US) | 2004-08-18 | — | — | EP | disclosed |
| EP-1446096-A1 | TOPICAL COMPOSITIONS CONTAINING ENZYMES STABILISED WITH INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2004-08-18 | — | — | EP | disclosed |
| US-20030175232-A1 | Compositions containing enzymes stabilized with certain osmo-protectants and methods for using such compositions in personal care | THE PROCTER & GAMBLE COMPANY | 2003-09-18 | — | — | US | disclosed |
| US-20030157088-A1 | Compositions containing enzymes stabilized with inhibitors having certain binding properties and methods for using such compositions in personal care | THE PROCTOR & GAMBLE COMPANY | 2003-08-21 | — | — | US | disclosed |
| WO-2003041667-A2 | COMPOSITIONS CONTAINING ENZYMES STABILIZED WITH CERTAIN OSMO-PROTECTANTS AND METHODS FOR USING SUCH COMPOSITIONS IN PERSONAL CARE | THE PROCTER & GAMBLE COMPANY (US) | 2003-05-22 | — | — | WO | disclosed |
| WO-2003041680-A1 | TOPICAL COMPOSITIONS CONTAINING ENZYMES STABILIZED WITH INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2003-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170260435-A1 | Biological Buffers with Wide Buffering Ranges | PEF1, SLC7A1, PLPBP | PTGS1 2181/4885PDE4A 20/4885LMNA 1639/4885 |
| US-20140073789-A1 | Biological Buffers with Wide Buffering Ranges | PEF1, SLC7A1, PLPBP | PTGS1 2181/4885PDE4A 20/4885LMNA 1639/4885 |
| US-20160280634-A1 | Biological Buffers with Wide Buffering Ranges | PEF1, SLC7A1, PLPBP | PTGS1 2181/4885PDE4A 20/4885LMNA 1639/4885 |
| US-20030175232-A1 | Compositions containing enzymes stabilized with certain osmo-protectants and methods for using such compositions in personal care | TREH, CUTA, LPO | PTGS1 2757/4885PDE4A 1687/4885LMNA 1798/4885 |
| US-20160194283-A1 | Biological Buffers with Wide Buffering Ranges | PEF1, SLC7A1, PLPBP | PTGS1 2181/4885PDE4A 20/4885LMNA 1639/4885 |
| US-20160369142-A1 | Biological Buffers with Wide Buffering Ranges | PEF1, SLC7A1, PLPBP | PTGS1 2181/4885PDE4A 20/4885LMNA 1639/4885 |
| US-20030157088-A1 | Compositions containing enzymes stabilized with inhibitors having certain binding properties and methods for using such compositions in personal care | CUTA, LCT, TYR | PTGS1 3207/4885PDE4A 1680/4885LMNA 599/4885 |
| US-20170313920-A1 | Biological Buffers with Wide Buffering Ranges | PEF1, SLC7A1, PLPBP | PTGS1 2181/4885PDE4A 20/4885LMNA 1639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.