SCHEMBL4198635

SCHEMBL4198635

C=CC(=O)OC(COc1ccccc1)CSc1ccc(Sc2ccc(SCC(COc3ccccc3)OC(=O)C=C)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.47
BACE1 P56817 1/20 0.39
PPARD Q03181 8/20 0.38
MMP3 P08254 1/20 0.36
MTNR1A P48039 3/20 0.35
MTNR1B P49286 3/20 0.35
NPC1 O15118 1/20 0.34
USP2 O75604 1/20 0.34
PPARA Q07869 1/20 0.34
LMNA P02545 1/20 0.34
TEAD1 P28347 1/20 0.34
TEAD3 Q99594 1/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4759193 0.94 THRB (0.47) THRBBACE1PPARDMMP3MTNR1A
SCHEMBL4200281 0.90 THRB (0.51) THRBMTNR1AMTNR1BPPARALMNA
SCHEMBL4190783 0.89 THRB (0.40) THRBBACE1PPARDMMP3MTNR1A
SCHEMBL6753001 0.88 MMP3 (0.47) THRBBACE1PPARDMMP3MTNR1A
SCHEMBL6752943 0.88 THRB (0.41) THRBPPARDMMP3
SCHEMBL13853211 0.86 THRB (0.48) THRBMTNR1AMTNR1BPPARALMNA
SCHEMBL4759204 0.86 PPARG (0.44) THRBBACE1MMP3NPC1PPARA
SCHEMBL6753149 0.86 BACE1 (0.50) THRBBACE1PPARDMMP3PPARA
SCHEMBL4758985 0.84 PPARD (0.39) BACE1PPARDPPARA
SCHEMBL6753008 0.83 AR (0.43) PPARDPPARAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1627867-B1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF MITSUI CHEMICALS INC (JP) 2016-01-20 EP disclosed
US-7534909-B2 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2009-05-19 US disclosed
US-20070078198-A1 (Meth) acrylic ester compound and use thereof MITSUI CHEMICALS, INC. (JP) 2007-04-05 US disclosed
EP-1627867-A1 (METH)ACRYLIC ESTER COMPOUND AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2006-02-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070078198-A1 (Meth) acrylic ester compound and use thereof METTL14, PAM, TAS2R41 THRB 1009/4885BACE1 4542/4885PPARD 3395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.