Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TTR | P02766 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | GABRP | O00591 | 1/20 | 0.48 |
| ▸ | GABRD | O14764 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.48 |
| ▸ | GABRE | P78334 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2268884 | 0.88 | MAPT (0.75) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL6933741 | 0.83 | TTR (0.67) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL6934221 | 0.81 | TTR (0.65) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL5846673 | 0.80 | MAPT (0.68) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL23051434 | 0.79 | ALDH1A1 (0.64) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL4919505 | 0.78 | MAPT (0.62) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL2265496 | 0.77 | TTR (0.62) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL9917228 | 0.77 | MAPT (0.59) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL10597544 | 0.77 | KMT2A (0.49) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL9666128 | 0.76 | LMNA (0.56) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095205-A1 | Method of Modification of Hyaluronic Acid by Means of (O-ACYL-O'-ALKYL Carbonate-Substituted Pyridine) Complex | CONTIPRO C (CZ) | 2012-04-19 | — | — | US | disclosed |
| EP-2408823-A1 | A METHOD OF MODIFICATION OF HYALURONIC ACID BY MEANS OF (O-ACYL-O'-ALKYL CARBONATE - SUBSTITUTED PYRIDINE) COMPLEX | Contipro C A.S. (CZ) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010105582-A1 | A METHOD OF MODIFICATION OF HYALURONIC ACID BY MEANS OF (O-ACYL-O'-ALKYL CARBONATE - SUBSTITUTED PYRIDINE) COMPLEX | CONTIPRO C A.S. (CZ) | 2010-09-23 | — | — | WO | disclosed |