Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904469 | 0.92 | ESR1 (0.45) | ESR1MEN1KMT2AMAPTCYP1B1 | |
| SCHEMBL2845203 | 0.88 | AKR1C1 (0.45) | ESR1MEN1KMT2AMAPTCYP2D6 | |
| SCHEMBL7944757 | 0.82 | ALDH1A1 (0.48) | ESR1MEN1KMT2AMAPTCYP2D6 | |
| SCHEMBL305384 | 0.80 | CYP19A1 (0.50) | CYP19A1MEN1KMT2ACYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL9803951 | 0.79 | CYP19A1 (0.49) | CYP19A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL27808829 | 0.77 | CYP1B1 (0.47) | MEN1KMT2ACYP3A4MAPTCYP1B1 | |
| SCHEMBL2126763 | 0.77 | CYP1B1 (0.52) | MEN1KMT2AMAPTMAOBCYP1B1 | |
| SCHEMBL2992588 | 0.75 | LCK (0.41) | ESR1MEN1KMT2AMAPTCES2 | |
| SCHEMBL2992590 | 0.75 | LCK (0.41) | ESR1MEN1KMT2AMAPTCES2 | |
| SCHEMBL8089190 | 0.75 | ESR1 (0.80) | ESR1ESR2CYP19A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841465-A4 | STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | UNIV PENNSYLVANIA (US) | 2009-04-01 | — | — | EP | disclosed |
| EP-1841465-A2 | STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | The Trustees of The University of Pennsylvania (US) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006066104-A2 | STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-06-22 | — | — | WO | disclosed |