Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.42 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9803951 | 0.98 | CYP19A1 (0.49) | CYP19A1CYP11B2KMT2AKDM4EPLOD2 | |
| SCHEMBL7904469 | 0.87 | ESR1 (0.45) | KMT2AALDH1A1CYP2D6MAPTMEN1 | |
| SCHEMBL2845203 | 0.87 | AKR1C1 (0.45) | KMT2AALDH1A1CYP2D6MAPTMEN1 | |
| SCHEMBL9804059 | 0.83 | CYP19A1 (0.47) | CYP19A1CYP11B2KMT2AKDM4EPLOD2 | |
| SCHEMBL4199808 | 0.80 | ESR1 (0.58) | CYP19A1KMT2ACYP3A4CYP2D6TDP1 | |
| SCHEMBL7944757 | 0.77 | ALDH1A1 (0.48) | KMT2AALDH1A1CYP2D6MAPTMEN1 | |
| SCHEMBL28255319 | 0.76 | CYP19A1 (0.55) | CYP19A1CYP11B2KMT2AKDM4EPLOD2 | |
| SCHEMBL2992588 | 0.74 | LCK (0.41) | KMT2AALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL4255052 | 0.74 | NPC1 (0.53) | KMT2AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL2992590 | 0.74 | LCK (0.41) | KMT2AALDH1A1HPGDMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814854-B1 | CATIONIC CERAMIDES, AND ANALOGS THEREOF, AND THEIR USE FOR PREVENTING OR TREATING CANCER | MUSC FOUND FOR RES DEV (US) | 2015-02-25 | — | — | EP | disclosed |
| US-8093393-B2 | Cationic ceramides, and analogs thereof, and their use for preventing or treating cancer | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2012-01-10 | — | — | US | disclosed |
| US-20110071099-A1 | Cationic Ceramides, And Analogs Thereof, And Their Use For Preventing Or Treating Cancer | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT | 2011-03-24 | — | — | US | disclosed |
| EP-1814854-A4 | CATIONIC CERAMIDES, AND ANALOGS THEREOF, AND THEIR USE FOR PREVENTING OR TREATING CANCER | MUSC FOUND FOR RES DEV (US) | 2009-08-05 | — | — | EP | disclosed |
| EP-1814854-A1 | CATIONIC CERAMIDES, AND ANALOGS THEREOF, AND THEIR USE FOR PREVENTING OR TREATING CANCER | MUSC Foundation For Research Development (US) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006050264-A1 | CATIONIC CERAMIDES, AND ANALOGS THEREOF, AND THEIR USE FOR PREVENTING OR TREATING CANCER | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2006-05-11 | — | — | WO | disclosed |
| EP-0828867-B1 | METHOD AND APPARATUS USING ORGANIC VAPOR PHASE DEPOSITION FOR THE GROWTH OF ORGANIC THIN FILMS WITH LARGE OPTICAL NON-LINEARITIES | UNIV PRINCETON (US) | 2003-01-08 | — | — | EP | disclosed |
| EP-0828867-A4 | METHOD AND APPARATUS USING ORGANIC VAPOR PHASE DEPOSITION FOR THE GROWTH OF ORGANIC THIN FILMS WITH LARGE OPTICAL NON-LINEARITIES | UNIV PRINCETON (US) | 1999-10-27 | — | — | EP | disclosed |
| EP-0828867-A2 | METHOD AND APPARATUS USING ORGANIC VAPOR PHASE DEPOSITION FOR THE GROWTH OF ORGANIC THIN FILMS WITH LARGE OPTICAL NON-LINEARITIES | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996041173-A1 | NANOPARTICLES IMPRINTED WITH RECOGNITION SITES FOR TARGET MOLECULES | MARTINEX R & D INC. (CA) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996037639-A2 | METHOD AND APPARATUS USING ORGANIC VAPOR PHASE DEPOSITION FOR THE GROWTH OF ORGANIC THIN FILMS WITH LARGE OPTICAL NON-LINEARITIES | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1996-11-28 | — | — | WO | disclosed |
| US-5554220-A | Method and apparatus using organic vapor phase deposition for the growth of organic thin films with large optical non-linearities | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1996-09-10 | — | — | US | disclosed |
| US-4987056-A | IMPROVED SENSITIVITY TO VISIBLE LIGHT | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1991-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071099-A1 | Cationic Ceramides, And Analogs Thereof, And Their Use For Preventing Or Treating Cancer | CERS2, CERT1, SGMS1 | CYP19A1 4460/4885CYP11B2 652/4885KMT2A 4686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.