Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2992588 | 1.00 | LCK (0.41) | LCKFYNDAOHPGDALDH1A1 | |
| SCHEMBL2992596 | 0.85 | MAPT (0.39) | LCKFYNDAOHPGDALDH1A1 | |
| SCHEMBL2845203 | 0.81 | AKR1C1 (0.45) | ALDH1A1GAATSHRAKR1C3AKR1C1 | |
| SCHEMBL7904469 | 0.81 | ESR1 (0.45) | ALDH1A1GAATSHRAKR1C3AKR1C1 | |
| SCHEMBL4199808 | 0.75 | ESR1 (0.58) | CES2ESR1MEN1KMT2AMAPT | |
| SCHEMBL8967280 | 0.74 | CES2 (0.44) | LCKFYNDAOHPGDALDH1A1 | |
| SCHEMBL305384 | 0.74 | CYP19A1 (0.50) | HPGDALDH1A1HTTMEN1KMT2A | |
| SCHEMBL7383322 | 0.72 | AKR1C1 (0.65) | LCKFYNDAOHPGDALDH1A1 | |
| SCHEMBL5457557 | 0.72 | AKR1C1 (0.65) | LCKFYNDAOHPGDALDH1A1 | |
| SCHEMBL7944757 | 0.72 | ALDH1A1 (0.48) | ALDH1A1GAATSHRAKR1C3CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781187-B2 | Fluorescent dyes | CORNING INCORPORATED (US) | 2010-08-24 | — | — | US | disclosed |
| EP-1973973-A2 | FLUORESCENT DYES | CORNING INCORPORATED (US) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007078926-A2 | FLUORESCENT DYES | CORNING INCORPORATED (US) | 2007-07-12 | — | — | WO | disclosed |
| US-20070154980-A1 | Fluorescent dyes | CORNING INCORPORATED | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070154980-A1 | Fluorescent dyes | ZYX, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, H1-0 | LCK 3509/4885FYN 3343/4885DAO 377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.