SCHEMBL4199940

SCHEMBL4199940

C=Cc1cc(C(C)C)ccc1OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
ERN1 O75460 2/20 0.41
NFE2L2 Q16236 2/20 0.40
ALDH1A1 P00352 7/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
POLB P06746 1/20 0.38
PPARG P37231 2/20 0.38
PPARD Q03181 2/20 0.38
PPARA Q07869 2/20 0.38
CYP1A2 P05177 2/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
KMT2A Q03164 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TRPA1 O75762 1/20 0.37
TYR P14679 1/20 0.37
HPGD P15428 1/20 0.37
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17072132 0.86 PPARG (0.36) ERN1NFE2L2ALDH1A1SMN1; SMN2PPARG
SCHEMBL2467985 0.85 HDAC4 (0.43) HDAC4HDAC8ERN1NFE2L2ALDH1A1
SCHEMBL985519 0.81 ERN1 (0.55) HDAC4HDAC8ERN1ALDH1A1SMN1; SMN2
SCHEMBL31063006 0.81 ERN1 (0.55) HDAC4HDAC8ERN1ALDH1A1SMN1; SMN2
SCHEMBL15003052 0.81 HDAC4 (0.40) HDAC4HDAC8ERN1NFE2L2ALDH1A1
SCHEMBL18088896 0.80 HMGCR (0.53) HDAC4HDAC8ERN1NFE2L2ALDH1A1
SCHEMBL18556286 0.80 MAPT (0.48) NFE2L2ALDH1A1SMN1; SMN2CYP1A2KMT2A
SCHEMBL13272121 0.79 MT-CO2 (0.44) ERN1ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL19237501 0.77 GABRA1 (0.52) ALDH1A1SMN1; SMN2PPARGPPARDPPARA
SCHEMBL19737439 0.77 HPGD (0.42) HDAC4HDAC8ERN1NFE2L2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115304757-B Block type ink resin and preparation method thereof 成都托展新材料股份有限公司 2023-08-11 CN claimed
CN-115304757-A Block type ink resin and preparation method thereof 成都托展新材料股份有限公司 2022-11-08 CN claimed
CN-115304757-B Block type ink resin and preparation method thereof 成都托展新材料股份有限公司 2023-08-11 CN disclosed
CN-115304757-A Block type ink resin and preparation method thereof 成都托展新材料股份有限公司 2022-11-08 CN disclosed
WO-2016131001-A9 PROCESS AND SYSTEM FOR PRODUCTION OF POLYPROPIOLACTONE NOVOMER INC. (US) 2017-07-13 WO disclosed
US-20170183369-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2017-06-29 US disclosed
US-20170096407-A1 CATALYST RECYCLE METHODS NOVOMER, INC. (US) 2017-04-06 US disclosed
US-20170073463-A1 CATALYTIC CARBONYLATION CATALYSTS AND METHODS NOVOMER, INC. (US) 2017-03-16 US disclosed
US-9403861-B2 Salen complexes with dianionic counterions NOVOMER, INC. (US) 2016-08-02 US disclosed
US-9327280-B2 Catalytic carbonylation catalysts and methods NOVOMER, INC. (US) 2016-05-03 US disclosed
US-8956989-B2 Catalysts and methods for polymer synthesis NOVOMER, INC. (US) 2015-02-17 US disclosed
US-7173084-B2 Levelling agent and anti-cratering agent EFKA ADDITIVES B.V. (NL) 2007-02-06 US disclosed
EP-1562696-B1 AQUEOUS EMULSION POLYMER AS DISPERSANT CIBA SC HOLDING AG (CH) 2006-03-29 EP disclosed
EP-1562696-A2 AQUEOUS EMULSION POLYMER AS DISPERSANT Efka Additives B.V. (NL) 2005-08-17 EP disclosed
US-20040236007-A1 Levelling agent and anti-cratering agent CIBA SPECIALTY CHEMICALS CORPORATION 2004-11-25 US disclosed
EP-1444302-A1 LEVELLING AGENT AND ANTI-CRATERING AGENT Efka Additives B.V. (NL) 2004-08-11 EP disclosed
WO-2004045755-A2 AQUEOUS EMULSION POLYMER AS DISPERSANT EFKA ADDITIVES B.V. (NL) 2004-06-03 WO disclosed
WO-2003033603-A1 LEVELLING AGENT AND ANTI-CRATERING AGENT EFKA ADDITIVES B.V. (NL) 2003-04-24 WO disclosed
US-4075237-A Perfluorinated esters of fumaric acid and certain other ethylenically unsaturated poly-basic acid and soil repellant polymers thereof GEIGY CHEMICAL CORPORATION (US) 1978-02-21 US disclosed
US-3949136-A OIL REPELLENTS, WATERPROOFING TEXTILES CIBA-GEIGY AG (CH) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170096407-A1 CATALYST RECYCLE METHODS CBR1, CBR3, EPHX2 HDAC4 2191/4885HDAC8 3565/4885ERN1 1009/4885
US-20170073463-A1 CATALYTIC CARBONYLATION CATALYSTS AND METHODS CBR3, CBR1, EPHX2 HDAC4 991/4885HDAC8 1748/4885ERN1 1374/4885
US-20170183369-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS PPOX, COASY, SOD1 HDAC4 1779/4885HDAC8 2107/4885ERN1 2610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.