Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 7/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4203655 | 0.88 | CCR5 (0.61) | CCR5OPRM1KCNH2TMEM97SIGMAR1 | |
| SCHEMBL4203659 | 0.84 | CCR5 (0.58) | CCR5OPRM1KCNH2 | |
| SCHEMBL13853354 | 0.82 | CCR5 (0.56) | CCR5OPRM1KCNH2 | |
| SCHEMBL13853365 | 0.81 | CCR5 (0.61) | CCR5OPRM1KCNH2 | |
| SCHEMBL4189593 | 0.81 | CCR5 (0.66) | CCR5OPRM1KCNH2 | |
| Hydrochloric Acid SCHEMBL4193534 | 0.80 | CCR5 (0.60) | CCR5OPRM1KCNH2 | |
| SCHEMBL4198203 | 0.79 | OPRM1 (0.62) | CCR5OPRM1KCNH2 | |
| SCHEMBL4193616 | 0.75 | OPRM1 (0.70) | CCR5OPRM1KCNH2 | |
| SCHEMBL4205420 | 0.74 | CCR5 (0.60) | CCR5OPRM1KCNH2 | |
| SCHEMBL13853351 | 0.73 | CCR5 (0.54) | CCR5OPRM1KCNH2TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124635-A1 | CHEMICAL COMPOUNDS | PFIZER INC. (GB) | 2009-05-14 | — | — | US | disclosed |
| US-20090124635-A1 | CHEMICAL COMPOUNDS | PFIZER INC. (GB) | 2009-05-14 | — | — | US | disclosed |
| US-20090124635-A1 | CHEMICAL COMPOUNDS | PFIZER INC. (GB) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124635-A1 | CHEMICAL COMPOUNDS | CCR5, CXCR3, CCR2 | CCR5 1/4885OPRM1 60/4885KCNH2 2799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.