SCHEMBL420063

SCHEMBL420063

Nc1ccc(OCC(F)(F)OC(F)(F)C(F)(F)OC(F)(F)C(F)(F)OC(F)(F)C(F)(F)F)cc1O

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.35
ALDH1A1 P00352 1/20 0.35
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MMP2 P08253 1/20 0.31
MMP14 P50281 1/20 0.31
CYP2C9 P11712 2/20 0.30
CYP1A2 P05177 1/20 0.30
CYP17A1 P05093 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7565445 0.79 LTA4H (0.39) MEN1KMT2ACYP1A2CYP2C19
SCHEMBL22382283 0.79 ALDH1A1 (0.52) MAPTALDH1A1KDM4EMEN1POLB
SCHEMBL7558830 0.78 CYP17A1 (0.40) MAPTMEN1GAARAB9AKMT2A
SCHEMBL7560691 0.75 ESR2 (0.39) CYP1A2CYP2C19
SCHEMBL7558569 0.73 CYP17A1 (0.36) MAPTGAARAB9ACYP2C9CYP1A2
SCHEMBL6973054 0.72 LTA4H (0.34) CYP1A2CYP2C19
SCHEMBL9122253 0.72 NPC1 (0.37) MAPTKDM4EMEN1RAB9AKMT2A
SCHEMBL22032571 0.72 POLB (0.50) MAPTKDM4EPOLB
SCHEMBL8542097 0.70 ESR2 (0.37) CYP1A2CYP2C19
SCHEMBL31339539 0.69 MEN1 (0.48) MAPTALDH1A1KDM4EMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9117475-B2 Lubricant composition and use thereof FUJIFILM CORPORATION (JP) 2015-08-25 US disclosed
EP-2412789-A1 LUBRICANT COMPOSITION AND USE THEREOF FUJIFILM Corporation (JP) 2012-02-01 EP disclosed
US-20120021253-A1 LUBRICANT COMPOSITION AND USE THEREOF FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120021253-A1 LUBRICANT COMPOSITION AND USE THEREOF MUC1, F12, SFN MAPT 3406/4885ALDH1A1 3731/4885KDM4E 4221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.