Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PNP | P00491 | 9/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4201094 | 0.79 | PNP (0.42) | PNPMEN1KMT2A | |
| Guanine SCHEMBL4198112 | 0.78 | PNP (0.58) | MAPTPNPMEN1KMT2A | |
| SCHEMBL22144 | 0.74 | MAPT (1.00) | MAPTPNPMEN1KMT2A | |
| SCHEMBL10607653 | 0.72 | PNP (0.39) | PNPMEN1KMT2ATLR7 | |
| SCHEMBL7029877 | 0.69 | ADORA2B (0.38) | MAPT | |
| SCHEMBL7031782 | 0.69 | ADORA2B (0.38) | MAPT | |
| Cytosine SCHEMBL4198774 | 0.69 | LMNA (0.38) | MAPTPNPMEN1KMT2A | |
| SCHEMBL2524005 | 0.68 | KDM4E (0.46) | MAPT | |
| SCHEMBL447389 | 0.68 | MAPT (0.84) | MAPTPNPMEN1KMT2A | |
| SCHEMBL23181030 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608402-B2 | DNA methylation specific signal amplification | LI WEIWEI | 2009-10-27 | — | — | US | disclosed |
| US-20090181373-A1 | DNA methylation specific signal amplification | LI WEIWEI | 2009-07-16 | — | — | US | disclosed |