Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.81 |
| ▸ | BACE1 | P56817 | 2/20 | 0.81 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4200691 | 0.99 | ACHE (0.80) | ACHEBACE1BCHE | |
| SCHEMBL24401463 | 0.96 | ACHE (0.89) | ACHEBACE1BCHE | |
| SCHEMBL8013133 | 0.90 | ACHE (1.00) | ACHEBACE1BCHE | |
| SCHEMBL3086109 | 0.90 | ACHE (1.00) | ACHEBACE1BCHE | |
| SCHEMBL29506653 | 0.90 | ACHE (1.00) | ACHEBACE1BCHE | |
| SCHEMBL1877163 | 0.90 | ACHE (1.00) | ACHEBACE1BCHE | |
| SCHEMBL29506655 | 0.90 | ACHE (1.00) | ACHEBACE1BCHE | |
| Hydrochloric Acid SCHEMBL4205699 | 0.89 | ACHE (0.98) | ACHEBACE1BCHE | |
| Hydrochloric Acid SCHEMBL29506654 | 0.89 | ACHE (0.98) | ACHEBACE1BCHE | |
| SCHEMBL14601859 | 0.89 | ACHE (0.89) | ACHEBACE1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107432-A1 | Sigma receptor binder containing indanone derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-05-19 | — | — | US | claimed |
| EP-1468684-A1 | SIGMA RECEPTOR BINDER CONTAINING INDANONE DERIVATIVE | Eisai Co., Ltd. (JP) | 2004-10-20 | — | — | EP | claimed |
| US-20090137629-A1 | Sigma receptor binding agent containing indanone derivative | IIMURA YOICHI | 2009-05-28 | — | — | US | disclosed |
| US-20090137629-A1 | Sigma receptor binding agent containing indanone derivative | IIMURA YOICHI | 2009-05-28 | — | — | US | disclosed |
| US-20090137629-A1 | Sigma receptor binding agent containing indanone derivative | IIMURA YOICHI | 2009-05-28 | — | — | US | disclosed |
| US-20050107432-A1 | Sigma receptor binder containing indanone derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-05-19 | — | — | US | disclosed |
| EP-1468684-A1 | SIGMA RECEPTOR BINDER CONTAINING INDANONE DERIVATIVE | Eisai Co., Ltd. (JP) | 2004-10-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137629-A1 | Sigma receptor binding agent containing indanone derivative | SIGMAR1, TMEM97, OPRK1 | ACHE 608/4885BACE1 3238/4885BCHE 1667/4885 |
| US-20050107432-A1 | Sigma receptor binder containing indanone derivative | SIGMAR1, OPRK1, TMEM97 | ACHE 2667/4885BACE1 4457/4885BCHE 3026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.