Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.51 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.51 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 1/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenine SCHEMBL4201626 | 0.84 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL29522302 | 0.80 | PI4KA (0.59) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL1577866 | 0.78 | LMNA (0.56) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Mercaptopurine Anhydrous SCHEMBL6897151 | 0.78 | SMN1; SMN2 (0.45) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL6162497 | 0.77 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL28186581 | 0.77 | PI4KA (0.67) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Glutamine SCHEMBL27878718 | 0.76 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Lysine SCHEMBL28077124 | 0.76 | PI4KA (0.54) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL9663406 | 0.75 | PI4KA (0.52) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL28129349 | 0.75 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8206931-B2 | Methods of identifying modulators of cellular glycosylation using GTRAP3-18 | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-06-26 | — | — | US | disclosed |
| EP-1595129-A4 | METHODS OF IDENTIFYING MODULATORS OF CELLULAR GLYCOSYLATION USING GTRAP3-18 | UNIV JOHNS HOPKINS (US) | 2009-03-04 | — | — | EP | disclosed |
| US-20060211042-A1 | Methods of identifying modulators of cellular glycosylation using gtrap3-18 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-09-21 | — | — | US | disclosed |
| EP-1595129-A2 | METHODS OF IDENTIFYING MODULATORS OF CELLULAR GLYCOSYLATION USING GTRAP3-18 | THE JOHNS HOPKINS UNIVERSITY (US) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004065932-A2 | METHODS OF IDENTIFYING MODULATORS OF CELLULAR GLYCOSYLATION USING GTRAP3-18 | THE JOHNS HOPKINS UNIVERSITY (US) | 2004-08-05 | — | — | WO | disclosed |