Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenine SCHEMBL6162502 | 0.86 | PI4KA (0.51) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL29522302 | 0.81 | PI4KA (0.59) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL28433553 | 0.78 | PI4KA (0.71) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL4201626 | 0.78 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL4201615 | 0.77 | PI4KA (0.51) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL1577866 | 0.76 | LMNA (0.56) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL28186581 | 0.73 | PI4KA (0.67) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Lysine SCHEMBL28077124 | 0.72 | PI4KA (0.54) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Glutamine SCHEMBL27878718 | 0.72 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL9663406 | 0.71 | PI4KA (0.52) | PI4KAPI4K2BPI4K2API4KBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501580-A1 | FILAMENTOUS EMBOLIZATION DEVICE AND METHOD OF USE | MicroVention, Inc. (US) | 2005-02-02 | — | — | EP | claimed |
| WO-2003090837-A1 | FILAMENTOUS EMBOLIZATION DEVICE AND METHOD OF USE | MICROVENTION, INC. (US) | 2003-11-06 | — | — | WO | claimed |
| US-20030199887-A1 | Filamentous embolization device and method of use | MICRO VENTION, INC. | 2003-10-23 | — | — | US | claimed |
| US-9795388-B1 | Surface configuration of implantable devices to modify biological activity and related method | EVANS, AVERY | 2017-10-24 | — | — | US | disclosed |
| EP-1501580-A1 | FILAMENTOUS EMBOLIZATION DEVICE AND METHOD OF USE | MicroVention, Inc. (US) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003090837-A1 | FILAMENTOUS EMBOLIZATION DEVICE AND METHOD OF USE | MICROVENTION, INC. (US) | 2003-11-06 | — | — | WO | disclosed |
| US-20030199887-A1 | Filamentous embolization device and method of use | MICRO VENTION, INC. | 2003-10-23 | — | — | US | disclosed |