Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.60 |
| ▸ | CCR5 | P51681 | 6/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13853361 | 1.00 | OPRM1 (0.60) | OPRM1CCR5KCNH2CHRM2CHRM3 | |
| SCHEMBL4199351 | 0.84 | OPRM1 (0.60) | OPRM1CCR5KCNH2CHRM2CHRM3 | |
| SCHEMBL13853358 | 0.84 | OPRM1 (0.60) | OPRM1CCR5KCNH2CHRM2CHRM3 | |
| SCHEMBL13853362 | 0.80 | MEN1 (0.52) | OPRM1CCR5KCNH2MEN1KMT2A | |
| SCHEMBL4193608 | 0.80 | MEN1 (0.52) | OPRM1CCR5KCNH2MEN1KMT2A | |
| SCHEMBL4193616 | 0.78 | OPRM1 (0.70) | OPRM1CCR5KCNH2CHRM2CHRM3 | |
| SCHEMBL4198203 | 0.78 | OPRM1 (0.62) | OPRM1CCR5KCNH2MEN1KMT2A | |
| SCHEMBL13853328 | 0.77 | CCR5 (0.56) | OPRM1CCR5KCNH2 | |
| SCHEMBL4132155 | 0.75 | SLC6A2 (0.60) | OPRM1CCR5KCNH2MEN1KMT2A | |
| SCHEMBL4138032 | 0.73 | CCR5 (0.65) | OPRM1CCR5KCNH2CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124635-A1 | CHEMICAL COMPOUNDS | PFIZER INC. (GB) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124635-A1 | CHEMICAL COMPOUNDS | CCR5, CXCR3, CCR2 | OPRM1 60/4885CCR5 1/4885KCNH2 2799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.