Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 14/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 13/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3694436 | 0.90 | SLC16A3 (0.39) | SLC16A3SLC16A1CTSA | |
| SCHEMBL3698138 | 0.86 | SLC16A3 (0.38) | SLC16A3SLC16A1MEN1KMT2ACNR1 | |
| SCHEMBL3692822 | 0.83 | SLC16A3 (0.35) | SLC16A3SLC16A1MEN1KMT2ACNR1 | |
| SCHEMBL3029599 | 0.82 | SLC16A3 (0.37) | SLC16A3SLC16A1P2RY1MEN1KMT2A | |
| SCHEMBL3701900 | 0.82 | SLC16A3 (0.37) | SLC16A3SLC16A1MEN1KMT2ACNR1 | |
| SCHEMBL3701339 | 0.81 | LMNA (0.36) | SLC16A3SLC16A1MEN1KMT2ACNR1 | |
| SCHEMBL3700573 | 0.79 | SLC16A3 (0.39) | SLC16A3SLC16A1CTSACNR1 | |
| SCHEMBL3701337 | 0.79 | SLC16A3 (0.36) | SLC16A3SLC16A1LMNAPDE4B | |
| SCHEMBL4201755 | 0.79 | SLC16A3 (0.36) | SLC16A3SLC16A1P2RY1MEN1KMT2A | |
| SCHEMBL2838853 | 0.78 | SLC6A4 (0.39) | LMNAPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009041705-A9 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2009-08-13 | — | — | WO | disclosed |